"Polyoxidonium" rau tus menyuam: tshuaj xyuas, cov lus qhia rau kev siv, muaj pes tsawg leeg thiab piav qhia

Cov txheej txheem:

"Polyoxidonium" rau tus menyuam: tshuaj xyuas, cov lus qhia rau kev siv, muaj pes tsawg leeg thiab piav qhia
"Polyoxidonium" rau tus menyuam: tshuaj xyuas, cov lus qhia rau kev siv, muaj pes tsawg leeg thiab piav qhia

Video: "Polyoxidonium" rau tus menyuam: tshuaj xyuas, cov lus qhia rau kev siv, muaj pes tsawg leeg thiab piav qhia

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Nyob hauv av thiab tsis txhob mob thaum lub caij khaub thuas thiab khaub thuas - qhov no yog lub luag haujlwm tseem ceeb ntawm peb ntau tus. Qhov teeb meem no ua tshwj xeeb tshaj yog thaum nws los txog rau cov menyuam yaus. Ntawm no koj yuav tsum nrhiav ntau yam tshuaj, qhov kev txiav txim uas tuaj yeem ntxiv dag zog rau lub cev tiv thaiv kab mob thiab ua kom lub cev tiv thaiv kab mob. Hauv qhov xwm txheej no, ntau tus niam txiv xaiv "Polyoxidonium" rau menyuam yaus, kev tshuaj xyuas hais tias tom qab nws siv, cov menyuam yaus tsis tshua muaj mob thiab pib mus kawm kindergarten tas li. Nws feem ntau tau sau los ntawm kws tshuaj tiv thaiv kab mob, tab sis tom qab kuaj xyuas tus menyuam kom zoo.

Cov tshuaj

"Polyoxidonium" rau menyuam yaus (kev tshuaj xyuas ntawm qee leej niam ua rau pom qhov tseeb tias cov tshuaj yuav tsum tau muab los ntawm tus kws kho mob tshwj xeeb thiab tsuas yog tom qab kawm cov tshuaj tiv thaiv kab mob) feem ntau yog sau rau hauv daim ntawv suppositories thiab qhuav hmoov rau npaj ib qho kev daws teeb meem. Cov menyuam yaus hnub nyoog tshaj kaum ob xyoos tuaj yeem noj tshuaj.

Ib tug dragee muaj 12 mg ntawm azoximer bromide. Cov khoom pab hauv cov ntsiav tshuaj yog stearic acid, lactose monohydrate thiabqos yaj ywm starch.

Lyophilisate rau kev tsim cov tshuaj ncua kev kawm muaj cov khoom xyaw nquag azoximer bromide. Muaj nyob rau hauv ntau npaum ntawm 3 mg thiab 6 mg. Cov khoom xyaw ntxiv yog betacarotene, mannitol thiab povidone.

Qhov chaw mos thiab qhov quav suppositories muaj azoximer bromide ntawm ib koob ntawm 6 mg thiab 12 mg. Lub hauv paus yog cocoa taum roj, nyob rau hauv tus nqi ntawm 1.3 g ib suppository. Cov tshuaj thib ob ntawm no yog cov khoom siv tib yam li hauv cov hmoov rau kev npaj cov tshuaj.

Kev tso tawm thiab piav qhia

polyoxidonium rau cov me nyuam tshuaj xyuas
polyoxidonium rau cov me nyuam tshuaj xyuas

"Polyoxidonium" rau menyuam yaus (kev tshuaj xyuas ntawm qee leej niam hais tias nws tsis zoo thiab cov menyuam yaus tseem mob tom qab siv nws li qub) muaj cov ntawv tso tawm hauv qab no, cov no yog:

  • tshuaj;
  • suppositories rau qhov quav thiab qhov chaw mos;
  • hmoov rau kev txhaj tshuaj thiab qhov ntswg.

Cov tshuaj hauv cov ntsiav tshuaj muaj nyob rau hauv hlwv ntawm 10 thiab 20 daim. Dragees yog pleev xim rau hauv cov xim dawb-daj. Lawv muaj kev pheej hmoo, chamfer thiab inscription "PO". Me me inhomogeneous inclusions tej zaum yuav raug soj ntsuam ntawm lawv nto.

Lyophilizate rau kev tsim cov tshuaj yog tsim nyob rau hauv ampoules thiab iav vials ntawm ib koob ntawm 4, 5 thiab 9 mg. Txhua lub cell muaj tsib ampoules lossis vials. Nyob rau hauv tag nrho, muaj 50 ampoules (vials) nyob rau hauv ib lub thawv ntawv. Pob ntawv no yog cim "rau tsev kho mob". Cov tshuaj yog hygroscopic thiab rhiab rau lub teeb.

Suppositories muaj lub ntsej muag torpedo thiab xim daj. Thaum siv lawv, koj tuaj yeem hnov qhov tsis hnov tsw tsw ntawm cocoa. Muaj tsib ntawm lawv nyob rau hauv ib lub hlwv. Muaj ob lub hlwv hauv pob.

Pharmacodynamics

polyoxidonium kev qhia tswm ciab rau menyuam yaus tshuaj xyuas
polyoxidonium kev qhia tswm ciab rau menyuam yaus tshuaj xyuas

"Polyoxidonium" rau menyuam yaus (kev tshuaj xyuas hais tias cov tshuaj pab txhawb kev kawm ntawm cov kab mob hauv cov kab mob broncho-pulmonary), cov kws kho mob qhia kom noj cov tshuaj tiv thaiv tsis muaj zog, vim tias qhov kev kho no yog immunostimulating thiab ua rau muaj kev tiv thaiv ntawm tus menyuam lub cev. rau qhov tshwm sim ntawm kev kis kab mob hauv zos thiab dav dav.

Cov tshuaj muaj qhov cuam tshuam ncaj qha rau phagocytic hlwb thiab cov neeg tua neeg ntuj. Txhawb kev tsim ntawm ntau cov tshuaj tiv thaiv kab mob. Nrog rov qab cov kab mob tiv thaiv kab mob, nws rov ua haujlwm tiv thaiv. Xws li cov nyhuv ntawm cov tshuaj tshwm sim nrog cov kab mob tshwm sim los ntawm kev raug mob, ntau yam kab mob, txheej txheem autoimmune, kub hnyiab, malignant neoplasms thiab mob hnyav tom qab phais. Tsis tas li ntawd, cov tshuaj tau muab rau cov neeg mob uas siv cov tshuaj steroid hormones, chemotherapeutic agents thiab cytostatics.

Ntxiv rau cov khoom siv tshuaj tiv thaiv kab mob, "Polyoxidonium" yog tus cwj pwm los ntawm kev tshem tawm cov tshuaj lom thiab antioxidant zog. Nws tshem tawm lub cev ntawm co toxins thiab ntsev ntawm cov hlau hnyav. Tshem tawm cov tshuaj tiv thaiv oxidative. Vim qhov no cuam tshuam rau lub cev, cov tshuaj tau ntse siv hauv kev kho mob ntawm cov neeg mob qog noj ntshav. Nyob rau hauv cov ntaub ntawv no, nws txo cov intoxication ntawm chemotherapy thiab radiotherapy, uas yuav pab kom tsis txhob muaj qhov tshwm sim ntawm cov txheej txheem no.

Teem sijhawm "Polyoxidonium" rov ua duaimmunodeficiency xeev ua rau kom muaj txiaj ntsig ntawm kev kho mob thiab txo nws lub sijhawm. Ua kom lub sijhawm tshem tawm qee yam kab mob thiab txo lub sijhawm siv tshuaj tua kab mob, tshuaj tua kab mob thiab glucocorticosteroids.

Cov tshuaj tau txais txiaj ntsig zoo, mitogenic, muaj cov haujlwm polyclonal thiab tau txais txiaj ntsig nrog cov khoom siv tshuaj tiv thaiv. Tsis cuam tshuam rau lub cev.

Cov lus qhia rau kev siv "Polyoxidonium"

polyoxidonium suppositories 6 mg rau menyuam yaus tshuaj xyuas
polyoxidonium suppositories 6 mg rau menyuam yaus tshuaj xyuas

Kev tshuaj xyuas rau cov menyuam yaus (tus nqi ntawm cov tshuaj hloov pauv ib txhiab rubles) hais tias cov tshuaj ua kom muaj kev tiv thaiv lub cev, thiab tus menyuam mob tsawg dua tom qab siv.

Rau cov menyuam mos, cov tshuaj tau muab tshuaj rau cov kab mob bacteriovirus thiab cov kab mob fungal nyob rau theem mob thiab mob ntev. Nws raug nquahu kom siv nyob rau hauv cov theem hnyav ntawm kev ua xua thiab nyob rau hauv cov ntaub ntawv ntawm toxicity ntawm lub cev. Lub hom phiaj yog bronchial hawb pob, nyuaj los ntawm cov kab mob ntawm cov kab mob ua pa sab saud. Cov tshuaj yog muab rau atopic dermatitis nrog purulent foci, dysbacteriosis thiab rau kev kho sai ntawm cov kab mob protracted. Nws yog siv los tiv thaiv qhov tshwm sim ntawm tus mob khaub thuas thiab SARS.

ntsiav tshuaj "Polyoxidonium": cov lus qhia rau kev siv

polyoxidonium cov lus qhia rau kev siv nqi tshuaj xyuas rau cov menyuam yaus
polyoxidonium cov lus qhia rau kev siv nqi tshuaj xyuas rau cov menyuam yaus

Nqe (xyuas cov menyuam yaus tsis tau qhia kom muab tshuaj rau lawv tus kheej, yam tsis tau sab laj nrog kws kho mob, vim qhov no yog cov tshuaj tiv thaiv kab mob muaj zog heev,uas tsis nkag siab) siab txaus rau qee leej niam thiab yog li ntawd tsis yog txhua tus muaj peev xwm yuav nws.

Cov tshuaj tau noj ob txoj hauv kev: qhov ncauj thiab sublingually. Cov tshuaj yog qaug cawv ib nrab teev ua ntej noj mov loj. Rau cov neeg laus, qhov koob tshuaj txhua hnub yog 24 mg ib hnub, thiab cov menyuam yaus hnub nyoog qis dua 12 xyoos yuav tsum haus tsis pub ntau tshaj 12 ml ib hnub. Cov tshuaj no tau muab 3 zaug hauv ib hnub.

Cov tshuaj tau muab tshuaj sublingually rau ntau yam kab mob ntawm lub qhov ncauj thiab pharynx. Qhov siab tshaj plaws txhua hnub koob tshuaj yog 24 mg, nws muab faib ua ob koob tshuaj, txhua tus uas dissolves 12 mg. Lub sijhawm nruab nrab ntawm kev noj tshuaj yuav tsum yog tsawg kawg 12 teev. Kev kho mob kav ntev txog 14 hnub.

Yog cov kab mob hauv qhov ncauj yog tshwm sim los ntawm kab mob herpetic thiab fungal thiab tau mob hnyav, ces cov tshuaj raug pom zoo kom noj 12 mg mus txog peb zaug hauv ib hnub. Lub sijhawm nruab nrab ntawm cov tshuaj yog yim teev.

Hauv kev mob otitis media thiab sinusitis, noj ib ntsiav tshuaj ob zaug ib hnub. Duration ntawm kev nkag 5-10 hnub.

Rau tus mob tonsillitis, yaj ib ntsiav tshuaj peb zaug hauv ib hnub, tswj lub sijhawm ntawm kev noj tshuaj sib npaug li yim teev. Duration ntawm kev kho mob mus txog ob lub lis piam.

Cov kab mob broncho-pulmonary yog kho nrog koob tshuaj 24 mg, uas yuav tsum tau noj hauv ob koob tshuaj. Hoob no kav ntev li ob lub lis piam.

Rau kev tiv thaiv kab mob khaub thuas thiab SARS, yog tias tus neeg mob mob ntau tshaj plaub zaug hauv ib xyoos, cov tshuaj siv ob zaug ib hnub. Kev kho mob kav ntev txog 15 hnub.

Kev noj qab haus huvcov ntsiav tshuaj tau raug sau tseg rau kev kho mob ntawm lub ntsws sab sauv. Ntawm no, rau cov neeg laus, tus qauv yog 24 mg (ob ntsiav tshuaj), rau cov menyuam yaus hnub nyoog 12 xyoos - 12 mg. Hoob kawm yog ob lub lis piam.

Yuav siv tswm ciab

polyoxidonium tshuaj xyuas rau cov me nyuam tus nqi
polyoxidonium tshuaj xyuas rau cov me nyuam tus nqi

Ntau zaus pom zoo rau menyuam yaus rau kev tiv thaiv tus mob khaub thuas suppositories rau qhov quav "Polyoxidonium". Cov lus qhia (cov tswm ciab rau cov menyuam yaus raug qhia kom nkag siab zoo, txij li lawv tau tso cai siv txij thaum muaj hnub nyoog 6 xyoos xwb, thiab thaum siv thaum muaj hnub nyoog ntxov lawv tau muab faib ua ob ntu) pom zoo nrog kws kho mob tham ua ntej siv tshuaj.

Cov tshuaj hauv daim ntawv no yog siv ib zaug thaum hmo ntuj, tab sis txhua kis yog tus kheej thiab lub sijhawm kho yog tswj hwm los ntawm tus kws tshaj lij. Cov tshuaj siv tau txhua hnub, nrog rau hauv ib hnub lossis ob hnub.

Raws li qhov ntau npaum, cov tshuaj "Polyoxidonium" muab faib ua ob pawg:

  • Suppositories 6 mg rau cov menyuam yaus (kev tshuaj xyuas ntawm qee tus neeg mob hais tias lawv tsis muaj txiaj ntsig zoo dua li kev txhaj tshuaj) raug tshuaj txij li hnub nyoog rau rau xyoo.
  • 12mg suppositories qhia los txhim kho kev tiv thaiv kab mob hauv cov neeg laus.

Yog tias cov tshuaj suppositories siv rectally, ces ua ntej qhia lawv mus rau hauv lub cev, cov hnyuv yog tag nrho. Intravaginally, cov tshuaj yog siv ib hmos.

Raws li txoj kev lees paub, suppositories, tsis hais ntau npaum li cas, yog siv ib hnub ib zaug, rau peb hnub. Yav tom ntej, tswm ciab yog siv txhua hnub. Cov kev kho mob muaj xws li 10-20 suppositories. Rov kho dua yog tias tsim nyogpeb mus rau plaub lub hlis tom qab.

Cov neeg mob uas muaj kev tiv thaiv kab mob tsis zoo, kev tiv thaiv kab mob tiv thaiv kab mob, kab mob oncology, thiab cov neeg muaj kab mob HIV tom qab kis tau yuav tsum tau siv cov tshuaj ntev ntev, txij li peb lub hlis mus rau ib xyoos. Ntawm no, tsis yog curative, tab sis kev txhawb nqa kev kho yog qhia ntau dua. Hauv qhov no, suppositories yog muab 1-2 zaug hauv ib lub lis piam.

Qhia siv cov hmoov

polyoxidonium tswm ciab rau cov me nyuam mus txog ib xyoos kev tshuaj xyuas
polyoxidonium tswm ciab rau cov me nyuam mus txog ib xyoos kev tshuaj xyuas

Muab "Polyoxidonium" rau lub qhov ntswg ntawm cov menyuam yaus (kev tshuaj xyuas hais tias qhov no yog ib qho cuab yeej zoo rau kev tiv thaiv kab mob khaub thuas thiab mob khaub thuas) nrog adenoids thiab lwm yam kab mob ntawm lub qhov ncauj kab noj hniav. Cov tshuaj tuaj yeem muab rau cov menyuam mos hauv parenterally thiab sublingually. Txoj kev tswj hwm thiab koob tshuaj yuav tsum raug xaiv los ntawm tus kws kho mob.

Nrog rau kev siv tshuaj intramuscular thiab intravenous, "Polyoxidonium" tau muab rau cov menyuam yaus, pib txij li hnub nyoog peb lub hlis, txhua hnub, txhua hnub lossis ob zaug txhua xya hnub, 100-150 mcg / kg. Nyob rau hauv tag nrho, 5-10 cov txheej txheem yuav tsum tau ua.

Nyob rau hauv cov xwm txheej ntawm cov txheej txheem inflammatory, cov tshuaj tau pom zoo kom muab tshuaj txhua hnub ntawm koob tshuaj tsis pub tshaj 100 mcg / kg. Duration ntawm kev kho mob -7 hnub.

Hauv cov kab mob ntev nrog cov txheej txheem inflammatory, cov tshuaj siv ntawm 150 mcg / kg, ob zaug txhua 7 hnub. Hoob - kaum txhaj tshuaj.

Yog tias muaj kab mob ua xua lossis ua xua-ua xua rau hauv daim ntawv mob hnyav, ces cov tshuaj siv rau hauv cov hlab ntsha (drip) ntawm 15 mcg / kg nrog rau lwm cov tshuaj tiv thaiv kab mob.

Rau tshuaj tiv thaiv mob hnyavmuab intramuscularly ntawm ib koob ntawm 100 mcg / kg. Kev so ntawm kev txhaj tshuaj yog 1-2 hnub, chav kawm yog 5 txheej txheem.

Txhawm rau npaj cov kua rau kev txhaj tshuaj intramuscular, 3 mg ampoule lossis iav vial yog yaj hauv 1 ml dej rau kev txhaj tshuaj, uas, yog tias tsim nyog, tuaj yeem hloov nrog 0.9% sodium chloride tov.

Rau cov tshuaj txhaj, 3 mg ampoule lossis iav vial yog diluted hauv 1.5-2 ml ntawm 0.9% sodium chloride.

Kev siv tshuaj tua kab mob thiab kev siv sublingual

polyoxidonium tee rau menyuam yaus tshuaj xyuas
polyoxidonium tee rau menyuam yaus tshuaj xyuas

tuaj yeem siv tsis yog rau kev txhaj tshuaj xwb, tab sis kuj tseem siv tshuaj intranasally, sublingually immunomodulating tus neeg saib xyuas "Polyoxidonium". Qhov ntswg tee rau cov menyuam yaus (kev tshuaj xyuas hais tias qhov kev tswj hwm ntawm cov tshuaj no tsis muaj txiaj ntsig zoo dua li kev txhaj tshuaj, tab sis maj mam, vim tias cov tshuaj no mob heev) feem ntau 150 mcg / kg yog siv rau 5-10 hnub, uas yog 1-3. tee ua ke rau ntawm sab laug thiab sab xis qhov ntswg lossis hauv qab tus nplaig, txhua peb teev.

tee ntawm "Polyoxidonium" rau cov menyuam yaus (kev tshuaj xyuas hais tias lawv tiv thaiv qhov tshwm sim ntawm tus kab mob thiab kis kab mob zoo) yog txhaj rau hauv txhua lub qhov ntswg 1-3 tee. Cov txheej txheem rov ua dua txhua 2-3 teev.

Rau tsib kilograms ntawm qhov hnyav yuav tsum yog tsib tee ntawm cov tshuaj ib hnub twg, uas yog 0.25 ml ntawm kev daws. Yog tias qhov hnyav ntawm tus menyuam yog 10 kg, ces kaum tee lossis 0.5 ml ntawm cov tshuaj raug muab rau nws. Yog li, kaum tsib tee lossis 0.75 ml ntawm lyophilisate yuav tsum poob ntawm qhov hnyav ntawm 15 kg, thiab nees nkaum tee lossis 1 ml ntawm cov tshuaj raug pom zoo rau lub cev hnyav ntawm 20 kg.

rauKev npaj ntawm kev daws ntawm 3 mg ntawm hmoov yog diluted nyob rau hauv 1 ml ntawm distilled dej. Koj tuaj yeem siv cov dej boiled zoo tib yam los npaj cov Polyoxidonium lyophilisate. Ib tee ntawm cov tshuaj muaj txog 150 micrograms ntawm azoximer bromide. Nws qhov concentration yog xam raws li tus menyuam lub cev qhov hnyav.

Cov tshuaj tiav tau muab tso rau hauv lub tub yees rau ib lub lis piam. Ua ntej siv, lub pipette nrog tov yog rhuab mus rau ib tug kub ntawm +20-25 ° C.

Contraindications thiab phiv

Cov tshuaj tsis ua rau muaj kev phiv. Qee zaum, tom qab txhaj tshuaj, tej zaum yuav muaj mob me ntsis hauv thaj chaw uas cov tshuaj txhaj rau hauv cov leeg.

Cov tshuaj yuav tsum tsis txhob siv thaum cev xeeb tub thiab thaum pub niam mis. Kev txwv tsis pub siv yog ib tus neeg intolerance rau cov khoom hauv cov khoom thiab lub hnub nyoog ntawm tus menyuam txog rau lub hlis.

Kev saib xyuas tshwj xeeb yuav tsum tau noj thaum siv cov tshuaj hauv cov neeg mob lub raum tsis ua haujlwm thiab cov menyuam yaus hnub nyoog qis dua 6 lub hlis.

Cov lus qhia tshwj xeeb

Qhia rau cov mob hauv cov leeg tom qab txhaj tshuaj, npaj Polyoxidonium hmoov nrog 25% kev daws ntawm procaine cov lus qhia rau kev siv, tshuaj xyuas cov menyuam yaus pom zoo muab cov tshuaj no rau lub cev nruj me ntsis raws li kws kho mob tau sau tseg, tab sis muab cov lus qhia rau kev siv. Tus neeg mob tsis muaj kev fab tshuaj rau procaine.

Thaum muab tshuaj rau hauv cov hlab ntsha, cov tshuaj tsis yog diluted hauv cov tshuaj muaj protein ntau.

Tus nqi

"Polyoxidonium" tsuas yog muag hauv khw muag tshuaj thiab tsuas yog tso tawm los ntawm cov tshuaj. Nqe nyob ntawmdaim ntawv tso tawm ntawm cov tshuaj yuav txawv. Yog li, cov hmoov rau kev npaj 3 mg tshuaj raug nqi txog 650 rubles rau tsib ampoules, thiab txog 1050 rubles yuav tsum tau them rau 6 mg ntawm cov tshuaj. Tus nqi ntawm qhov chaw mos thiab qhov quav suppositories nrog ib koob ntawm 6 mg yog hais txog 800 rubles, thiab 950 rubles yuav tsum tau them rau 12 mg suppositories. Tus nqi ntawm ib pob ntawm kaum ntsiav tshuaj yog 750 rubles.

Reviews

Feem ntau sau rau cov mob khaub thuas ntev thiab mob hnyav "Polyoxidonium" rau cov menyuam yaus, cov kws kho mob hais tias qhov no yog ib qho khoom siv tseem ceeb hauv kev kho mob ntawm ntau yam kab mob. Cov tshuaj tsis ua rau muaj kev phiv thiab yooj yim zam los ntawm cov neeg mob. Txoj kev kho mob rau txhua tus neeg mob raug xaiv ib tus zuj zus.

tswm ciab "Polyoxidonium" rau cov menyuam yaus hnub nyoog qis dua ib xyoos (kev tshuaj xyuas qhia tias nws muaj txiaj ntsig zoo rau lub cev thiab nco ntsoov txo qis lub sijhawm ntawm tus kabmob thaum noj cov tshuaj no) tau qhia kom ua haujlwm ceev faj.

Ntau tus niam txiv hais tias cov tshuaj txhim kho kev tiv thaiv kab mob, txo lub sijhawm ntawm tus kabmob. Nws raug sau tseg tias kev txhaj tshuaj zoo tshaj plaws, txawm hais tias lawv mob heev thiab tsis yog txhua tus menyuam tuaj yeem tiv taus lawv. Ua tib zoo saib xyuas qhov tseeb tias qhov no yog cov tshuaj muaj zog thiab nws yuav tsum tau muab tshuaj los ntawm tus kws kho mob tom qab kawm txog immunogram. Cov niam txiv qhia kom tsis txhob maj mus yuav nws thiab pom zoo kom kuaj tshuaj rhiab heev.

Cov kev xav tsis zoo txog cov tshuaj hais tias nws tsis muaj txiaj ntsig zoo rau lub cev thiab yog cov placebo. Lawv nco txog nws tus nqi siab thiab tsis muaj kev tshawb fawb. Nws tau thov tias nws tuaj yeem ua rau muaj kev phom sij rau lub cev tiv thaiv kab mobtus me nyuam thiab cuam tshuam nrog kev tsim cov haujlwm tiv thaiv ntuj.

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