Migraine yog ib qho teeb meem rau ntau tus neeg mob. Yuav luag txhua tus neeg mob taub hau tsawg kawg ib zaug hauv lawv lub neej. Raws li txoj cai, lawv tau nrog kiv taub hau, xeev siab, ntuav, nrog rau loog, tingling thiab tsis muaj zog hauv cov ceg, yees duab- thiab phonophobia. Tom qab kev tawm tsam, cov neeg mob yws yws ntawm kev qaug zog, qaug zog thiab qaug zog. Qee lub sij hawm muaj cov xwm txheej thaum tus kab mob siab heev uas tsuas yog triptans rau mob taub hau tuaj yeem pab tus neeg mob. Nws yog ib nqi sau cia hais tias migraine yog ib tug kab mob ntawm cov poj niam, raws li lawv muaj kev cuam tshuam rau qhov no pathology ntau tshaj li cov txiv neej. Kwv yees li ntawm 10-18% ntawm cov neeg laus raug kuaj mob migraine.
mob taub hau yog paub rau sawv daws
Neeg feem coob tsis nrhiav kev pab los ntawm kws kho mob, tab sis sim tiv thaiv tus kab mob ntawm lawv tus kheej, thaum noj tshuaj loog. Nws yuav tsum tau hais tias txoj kev no tsis pab, tab sis tsuas yog exacerbates tus kab mob. Kev siv tsis tauanalgesics tuaj yeem ua rau muaj kev loj hlob ntawm cov tshuaj ua rau mob taub hau ntev. Yog li ntawd, nws tsis yog qhov xav tsis thoob tias muaj ntau cov lus nug txog cov tshuaj mob taub hau twg zoo tshaj plaws.
Nws yog qhov tsis muaj tseeb kom rov zoo los ntawm migraine, tab sis koj tuaj yeem txhim kho lub neej zoo nrog kev pab los ntawm cov tshuaj tshwj xeeb uas kws kho mob hlwb. Txog niaj hnub no, ntau cov kev kho mob migraine tau paub tias muaj txiaj ntsig zoo ob qho tib si thaum muaj kev tawm tsam thiab lub sijhawm ntawm kev tawm tsam. Tom ntej no, peb yuav ua tib zoo saib cov tshuaj migraine: daim ntawv teev cov tshuaj tiv thaiv thiab kev kho interictal. Triptans tau raug pov thawj tias yog cov tshuaj zoo tshaj plaws los kho mob taub hau. Rau kev tiv thaiv kab mob, cov tshuaj hauv qab no tau muab tshuaj:
- β-blockers;
- tshuaj tiv thaiv kev nyuaj siab;
- antiemetic;
- Y dej-soluble vitamins B;
- calcium blockers;
- anticonvulsants.
Kev lees txais tag nrho cov npe tshuaj saum toj no yuav tsum raug sau los ntawm tus kws tshaj lij tshwj xeeb.
Vim li cas kuv lub taub hau mob?
Ua ntej nkag siab tias triptans ua haujlwm li cas tiv thaiv kev mob taub hau, tus nqi ntawm qhov nyob ntawm cov chaw tsim khoom, nws yuav tsum nkag siab txog cov txheej txheem ntawm pathology. Mob taub hau tshwm sim vim khaus ntawm cov receptors ntawm meninges thiab cerebral hlab ntsha. Nrog kev ncab ntau dhau thiab dhau ntawm cov hlab ntsha, tshwj xeeb tshaj yog cov hlab ntsha uas nyob hauv lub xeev hypotonic, txhim kho.mob hnyav, uas tsuas yog tshem tawm nrog kev pab los ntawm cov kws kho mob tshwj xeeb. Ntau tus kws tshawb fawb uas tau nrhiav tshuaj kho mob migraine tau ntev tau los xaus tias triptans yog cov tshuaj zoo tshaj plaws rau kev tshem tawm cov kab mob no.
khoom ntawm triptans
Qhov kev txiav txim ntawm cov tshuaj yog tsom rau kev nqaim cov hlab ntsha ntawm lub hlwb. Triptan yog ib yam tshuaj uas ua rau lub nuclei thiab receptors ntawm lub paj hlwb trigeminal, uas, nyob rau hauv lem, txo qhov rhiab heev ntawm qhov mob. Triptans yog niaj hnub tshuaj tiv thaiv kab mob migraine uas muaj kev xaiv siab rau cov hlab ntsha ntawm dura mater encephali thiab ib qho kev xaiv tsis zoo rau cov hlab ntsha thiab cov hlab ntsha.
Tshuaj siv tshuaj zoo txo qhov mob ntawm theem ntawm tus txha caj qaum ntawm cov hlab ntsha trigeminal. Ntxiv rau tag nrho cov saum toj no, triptans yog cov tshuaj uas tuaj yeem tsis tsuas yog txo qhov zaus ntawm kev rov qab los ntawm cov kab mob pathology, tab sis kuj tshem tawm nws cov kev mob tshwm sim (piv txwv li, xeev siab, ntuav, suab thiab photophobia).
Cov txiaj ntsig tseem ceeb ntawm Triptans
Lawv cov khoom siv tshuaj muaj xws li kev ceev ntawm kev tau txais txiaj ntsig. Lus tom qab ib nrab teev, cov tsos mob ntawm qhov zoo ntawm cov tshuaj ntawm tus neeg mob lub cev raug soj ntsuam. Cov nyhuv kho mob tseem nyob thoob plaws qhov kev tawm tsam migraine. Hauv feem coob ntawm cov neeg mob, mob taub hau tsis tshwm sim.
Nyob hauv pebTau ob peb hnub, cov kws tshawb fawb tau ua pov thawj tias thaum pom cov cim ceeb toom ntawm kev tawm tsam, triptans rau migraine yuav tsum tau noj tam sim ntawd. Yav dhau los, muaj ib txoj kev xav tias kev mob migraine yuav tsum tau kho nyob rau theem, pib nrog kev noj tshuaj yooj yim.
tshuaj migraine: ib daim ntawv teev cov tshuaj nrov tshaj plaws
Pab pawg triptan suav nrog cov tshuaj hauv qab no:
- Zomig.
- "Amigrenin".
- Sumatriptan.
- Imigran.
- Relpax.
- Trimigren.
- Sumamigren.
- "Rapimed".
- Almotriptan.
- Naramig.
- Naratriptan.
- Frovatriptan.
- YZolmitriptan.
Cov nyhuv ntawm cov tshuaj rau txhua tus neeg mob tuaj yeem nruj me ntsis rau tus kheej, yog li txhawm rau txheeb xyuas qhov ua tau zoo ntawm cov tshuaj tshwj xeeb, cov kws kho mob pom zoo kom sim nws rau peb qhov kev tawm tsam migraine. Cov tshuaj tryptamine yog tus cwj pwm los ntawm bioavailability siab, lawv yooj yim thiab ceev nrooj kov yeej cov ntshav-hlwb barrier, thiab zoo nres migraine tawm tsam txawm nyob rau theem mob. Nws raug nquahu kom sau cov tshuaj no rau cov neeg mob uas muaj mob hnyav thiab mob hnyav.
Cov lus qhia rau kev siv
Ntau zaus peb hnov tib lo lus nug: cov tshuaj mob taub hau twg zoo tshaj? Cov kev tshawb fawb sim tau pom tias triptans yog kev kho mob zoo tshaj plaws rau cov tsos mob migraine. Migraine triptans yog qhov zoo tshaj plaws thaum nojnrhiav pom thawj cov cim qhia ntawm kev tawm tsam. Qhov siab tshaj plaws analgesic nyhuv yog pom nyob rau hauv ob teev tom qab noj cov tshuaj. Ua ntej noj cov tshuaj, ua tib zoo nyeem cov lus qhia thiab sab laj nrog koj tus kws kho mob. Nws yog ib qho tseem ceeb heev kom tsis txhob overdose ntawm cov tshuaj. Migraine triptans tsis pom zoo siv nrog tshuaj tua kab mob, tshuaj tua kab mob, tshuaj tua kab mob, lossis ua ke nrog tshuaj tiv thaiv kev nyuaj siab.
Txhawm rau ua tiav qhov xav tau, cov neeg mob yuav tsum ua raws li cov lus pom zoo hauv qab no rau kev noj triptans:
- Rau mob taub hau me me mus rau nruab nrab, noj 1 ntsiav tshuaj (los yog ib qho tshuaj tsuag);
- koob thib ob ntawm cov tshuaj tsis pub dhau 2 teev tom qab;
- hnub koj yuav tsum tsis txhob noj ntau tshaj ob koob;
- Triptans tsis pom zoo rau ntau tshaj ob hnub hauv ib lub lis piam.
cov khoom noj uas muaj thyramine yuav tsum tsis suav nrog koj cov zaub mov thaum lub sijhawm kho:
- cocoa;
- chocolate;
- taum;
- qe;
- celery;
- citrus;
- khoom noj khoom haus ntxiv;
- cheeses;
- txiv lws suav;
- txiv ntseej;
- yuav haus dej cawv.
Tsis txhob noj mov txias.
Yog mob migraine tshwm sim, triptan, tus nqi uas yuav qhia hauv qab no, kuj tuaj yeem siv nrog lwm cov tshuaj, xws li domperidone lossis metoclopramide.
Side effects
Thaum siv tshuaj ntau dhau, cov neeg mob ntsib cov teeb meem hauv qab no:
- kiv taub hau;
- anaphylactic shock;
- xav txhav;
- nausea;
- xav sov;
- mob plab hnyuv, plab hnyuv;
- ntua;
- dry mouth;
- myalgia;
- mob plab;
- drowsy;
- kub hnyiab ntawm daim tawv nqaij;
- Quicke's edema;
- tachycardia;
- urticaria;
- polyuria;
- muscle qaug zog;
- txoov siab;
- kev tsis haum xeeb;
- mob plab;
- tso zis ntau zaus;
- Spasm ntawm cov hlab ntsha coronary.
Txawm hais tias tag nrho cov no, migraine triptans yog ib qho kev kho sai sai. Yog tias qhov ntau npaum li cas thiab zaus ntawm kev noj cov tshuaj raug pom, qhov kev pheej hmoo ntawm kev mob tshwm sim tsawg heev. Feem ntau, tag nrho cov triptans tau txais txiaj ntsig zoo los ntawm lub cev. Cov kev mob tshwm sim, yog tias lawv tshwm sim, qhia me ntsis thiab ploj mus tsis muaj kev kho mob. Lub ntsiab tsis zoo ntawm triptans yog lawv cov nqi. Hmoov tsis zoo, tsis yog txhua tus neeg mob tuaj yeem them tau cov tshuaj no.
YContraindications
Migraine triptans tsis pom zoo rau cov xwm txheej hauv qab no:
- stroke;
- Yangiospastic angina;
- xeeb tub;
- kev huam yuaj cerebrovascular;
- lub sijhawm pub mis niam;
- coagulopathy (txhim kho cov ntshav txhaws);
- teenage xyoo;
- pathology ntawm lub plawv plawv;
- hypersensitivity raubioactive tshuaj ntawm cov tshuaj;
- tsis muaj kev kub ntxhov;
- arrhythmias;
- kab mob siab thiab raum;
- - Atherosclerosis.
Ua ntej sau qee yam triptans, tus kws kho mob tuaj koom yuav tsum txheeb xyuas qhov muaj feem cuam tshuam rau atherosclerosis. Cov xwm txheej no suav nrog cov hauv qab no:
- mob ntshav qab zib mellitus;
- poj niam tom qab menopausal;
- smoking;
- mob ntshav siab;
- obesity;
- qib siab ntawm cov roj cholesterol hauv cov ntshav;
- hnub nyoog tshaj 40 rau txiv neej;
- genetic predisposition rau lub plawv nres.
Qee tus neeg mob uas muaj kev pheej hmoo yuav tsum tau txais lawv thawj koob tshuaj tryptamine nyob rau hauv kev saib xyuas tshwj xeeb thiab kev saib xyuas ECG.
kev kho mob migraine
Muaj cov qauv kev kho mob dav dav rau kev kho tus kab mob uas ua kom pom tseeb rau lawv tus kheej feem ntau:
- kev kho mob yuav tsum pib nrog kev siv tshuaj tua kab mob lossis lawv cov kev sib xyaw ua ke (xws li cov tshuaj tsis-steroidal anti-inflammatory);
- yog tias kev siv tshuaj tua kab mob tsis tau txais txiaj ntsig zoo, tom qab 45 feeb koj yuav tsum noj triptan;
- yog tias triptan tsis ua haujlwm, tom qab ntawd hauv kev tawm tsam tom ntej koj yuav tsum siv lwm yam tshuaj los ntawm pawg triptan;
- Cov tshuaj uas tsis yog-steroidal anti-inflammatory yuav tsum tau siv rau kev mob taub hau atypical.
Kev siv cov kev kho mob migraine niaj hnub raws li triptans pab ua kom lub neej yooj yim dua rau ntau tus neeg mob. Tsis yogNws yog ib qho tsim nyog nco ntsoov tias koj tuaj yeem noj cov tshuaj no raws li kws kho mob tau sau tseg thiab tsuas yog nrog kev kuaj mob. Muaj cov xwm txheej thaum triptans thiab lwm yam tshuaj tsis haum tshwj xeeb tsis muab cov txiaj ntsig xav tau thiab tsis tshem tawm qhov mob. Hauv qhov no, cov kws kho mob, raws li txoj cai, tau sau cov kev kho mob nyuaj nrog kev siv tshuaj anticonvulsant, nrog rau beta-blockers. Cov tshuaj no suav nrog cov tshuaj hauv qab no:
- Penbutolol.
- "Txhob siab".
- Betaxolol.
- "Topiramate".
- Phenobarbital.
- Timolol.
- YPropranolol.
- "Labetanol".
- Bellataminal.
- Metoprolol.
- Topamax.
- Acebutalol.
Neurontin Neurontin
Yuav ua li cas txo qhov qaug dab peg?
Txhawm rau txo qhov zaus ntawm migraine tawm tsam, cov neeg mob yuav tsum ua raws li cov cai hauv qab no:
- noj tsis tu ncua;
- tshem tawm cov khoom noj thiab dej haus uas ua rau qaug dab peg (npias, chocolate, cheeses, champagne, citrus txiv hmab txiv ntoo, cawv liab) los ntawm koj cov zaub mov;
- txiav luam yeeb;
- nyob sab nraum kom ntau li ntau tau;
- zam kev ntxhov siab;
- ua kis las (ua luam dej yog qhov zoo tshaj);
- zam kev taug kev ntev ntawm tsheb npav, nkoj, tsheb.
Headache triptans: nqe
Triptans yog tsim nyob rau hauv ntau hom tshuaj: txhaj tshuaj, tshuaj tsuag qhov ntswg, ntsiav tshuaj, qhov quav suppositories. Daim ntawv no cuam tshuam tus nqi ntawm cov tshuajtso tawm, ntau npaum li cas, tus naj npawb ntawm cov ntsiav tshuaj hauv pob. Yog li ntawd, tus nqi ntawm cov tshuaj no txawv nyob rau hauv ntau yam - 150-1500 rubles ib pob.
