Calprotectin hauv quav - yog dab tsi? Qhov no yog cov protein uas tso tawm los ntawm leukocytes (macrophages thiab neutrophils) thaum lawv qhib lossis tua. Nws ua hauj lwm raws li ib tug cim qhia ntawm inflammatory dab tshwm sim nyob rau hauv txoj hnyuv. Qhov ntsuas ntau ntawm txoj kev tshawb no yog ncaj qha proportional rau cov leukocytes hauv txoj hnyuv.
Calprotectin hauv quav - yog dab tsi?
Cov tshuaj no tsuas yog tso tawm los ntawm cov kab mob leukocytes (neutrophils) lossis cov neeg tuag lawm. Qhov tseeb, nws yog ib qho protein ntau neutrophil lossis cov protein txuam nrog calcium. Calprotectin nyob rau hauv quav - dab tsi yog nws thiab nyob rau hauv dab tsi tshwm sim nyob rau hauv cov hnyuv?
Hauv kab mob plab hnyuv, tus lej ntawm leukocytes hauv nws nce. Leukocytes, uas yog neutrophils, sib ntaus sib tua, vim lawv tuag. Thaum lawv tuag, cov protein raug tso tawm - calprotectin, thiab qhov no ua rau nws cov concentration ntau ntxiv hauv cov quav.
DefinitionCov ntsiab lus ntau ntawm calprotectin hauv cov quav yog ib txoj hauv kev yooj yim thiab tsis cuam tshuam rau kev kuaj mob plab hnyuv (IBD). Qhov kev kuaj mob no tso cai rau tus kws kho mob tuaj koom sib txawv IBD los ntawm kev chim siab plob tsis so tswj, uas tsis yog tus cwj pwm los ntawm kev mob ntawm cov mucous membrane ntawm txoj hnyuv (GIT).
Thaum teem caij?
Txoj kev tshawb no raug txiav txim yog tus neeg mob muaj lus tsis txaus siab hauv qab no:
- cov quav tsis xwm yeem nrog hnoos qeev hauv lawv.
- Cov quav quav nrog ntshav hauv lawv.
- mob plab thiab ua npaws.
- tawm hws ntau dhau.
- Sudden weight loss.
- Kev qaug zog thiab qaug zog nrog kev ua si lub cev me me.
- Kev ua txhaum txoj hnyuv motility.
- rau xeev siab thiab ntuav.
- rau cem quav.
- Thaum tus neeg mob muaj pathologies hauv cheeb tsam perinatal, xws li abscesses lossis fistulas.
- Nyob rau hauv cov menyuam yaus uas muaj kev loj hlob qeeb.
Calprotectin hauv quav: ib txwm
Tus nqi ntawm qhov ntsuas no hauv cov quav ib txwm nyob ntawm 0 txog 10 mg / ml. Yog tias qib calprotectin hauv cov quav nyob hauv cov kev txwv no, qhov no txhais tau tias tus neeg mob tsis muaj IBD. Lub plab hnyuv mucosa tsis yog o. Thiab yog tias tus neeg mob tseem yws yws txog cov teeb meem ntawm plab hnyuv thiab cov quav xoob, qhov no yuav txhais tau tias nws muaj cov plab hnyuv siab raum. Tej zaum yuav muaj kev ntsuam xyuas ntxiv kom paub meej qhov kev kuaj mob.
qhov nce hauv calprotectin txhais li cas
Yog tias calprotectin hauv cov quav nce siab, qhov ua rau tuaj yeem cuam tshuam tsis yog nrog IBD, tab sis kuj nrog cov kab mob los yog kab mob ntawm txoj hnyuv, piv txwv li, salmonellosis, campylobacteriosis. Cov tshuaj tiv thaiv zoo sib xws tuaj yeem muab tau los ntawm kev muaj tus kab mob rotavirus, adenovirus lossis norovirus kab mob. Tsis tas li ntawd, calprotectin nyob rau hauv cov quav yuav nce siab nrog kev tsis haum tshuaj rau nyuj cov mis nyuj los yog kab mob celiac (tsis kam rau gluten muaj nyob rau hauv cereals), nrog rau muaj cov neoplasms, plab hnyuv diverticula los yog cystic fibrosis (ib hom kab mob cuam tshuam nrog kev puas tsuaj. mus rau cov qog endocrine ntawm sab nraud secretion).
Kev kawm tau ua li cas?
Xav txog thaum txoj kev tshawb fawb tau txiav txim kom pom calprotectin hauv cov quav. Nws yog dab tsi, peb twb paub lawm.
Txoj kev tshawb no yog sau rau cov neeg mob:
- Raws li kev tiv thaiv thaum kuaj mob.
- Rau qhov kev ua xyem xyav ntawm IBD.
- rau plab hnyuv los ntshav.
- Thaum tus neeg mob yws qhov mob plab thiab daim duab kho mob sib xws.
- Rau qhov kev kuaj mob sib txawv ntawm lub plab zom mov.
Yuav ua li cas?
Yog tias nws tau pom tias calprotectin hauv cov quav tau nce siab, tus kws kho mob yuav tsum txiav txim siab vim li cas rau qhov kev tshwm sim no. Txawm li cas los xij, koj yuav tsum tsis txhob koom nrog kev noj tshuaj rau tus kheej, vim. Nws tuaj yeem ua tus kab mob hnyav heev. Rau tus kws kho mobmuaj peev xwm kuaj tau kom raug, qee zaum kev tshawb fawb ntxiv yuav xav tau:
- Coprogram.
- Gregersen cov tshuaj tiv thaiv, lossis kuaj ntshav fecal occult. Xws li kev tshuaj ntsuam yuav tsum tau npaj tshwj xeeb. Rau peb hnub, tus neeg mob yuav tsum tsis txhob noj nqaij thiab ntses tais, nrog rau cov khoom noj uas muaj hlau (siab, qe, currants dub, chocolate).
- C-reactive protein nrog cov txheej txheem rhiab heev uas yuav tso cai rau koj los ntsuas qhov tshwm sim.
- Rheumatoid factor.
- CEA (cancer embryonic antigen).
- ANA (antibodies rau nuclear antigens).
- Ua tiav cov ntshav suav nrog yuav tsum suav leukocyte.
Kev kho mob
Yog li, tus kws kho mob tau kuaj pom tseeb, uas muaj cov tsos mob ntawm kev mob plab hnyuv mucosa, thiab tib lub sijhawm, calprotectin hauv cov quav tau nce siab. Kev kho mob yuav nyob ntawm qhov ua rau mob.
Yog tias muaj kab mob sib kis, xws li salmonellosis, yuav tsum tau txais kev kho mob uas tuaj yeem rhuav tshem tus kab mob (salmonella). Koj yuav tsum tau siv sij hawm sorbents, piv txwv li, Liferan, Dawb Thee, Enterodez, Smekta, thiab lwm yam Nyob rau hauv tas li ntawd, cov tshuaj yuav tsum tau mus muab lub dej-ntsev tshuav nyiaj li cas: Oralit, Regidron, etc. Nrog me me daim ntawv ntawm salmonellosis, feem ntau tshuaj tua kab mob tsis tau sau tseg, tk. Cov kab mob no tiv thaiv lawv.
Thaum tus kab mob no kis tau (adenovirus lossis rotavirus, thiab lwm yam), koj yuav xav tautshuaj tiv thaiv kab mob. Nws tuaj yeem yog "Arbidol", "Gordoks", "Virazole", thiab lwm yam. Immunostimulating thiab immunomodulating tshuaj "Cycloferon", "Anaferon", "Interferon" yog siv.
Tshuaj tua kab mob feem ntau yog muab los kho cov kab mob hauv plab. Piv txwv li, lawv tau sau ntawv "Ftalazol", thiab rau cov menyuam yaus lawv siv cov tshuaj tua kab mob uas muaj kev nyab xeeb tshaj plaws nrog ntau qhov kev ua "Cefix".
Enzistal thiab Festal enzymatic npaj muab cov txiaj ntsig zoo.
Tab sis tsuas yog tus kws kho mob yuav tsum tau sau ntawv kho mob, nyob ntawm tus neeg mob tus yam ntxwv thiab nws tus mob.
