Nicotinic acid: muaj pes tsawg leeg, khoom, lub hom phiaj thiab cov lus qhia rau kev siv

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Nicotinic acid: muaj pes tsawg leeg, khoom, lub hom phiaj thiab cov lus qhia rau kev siv
Nicotinic acid: muaj pes tsawg leeg, khoom, lub hom phiaj thiab cov lus qhia rau kev siv

Video: Nicotinic acid: muaj pes tsawg leeg, khoom, lub hom phiaj thiab cov lus qhia rau kev siv

Video: Nicotinic acid: muaj pes tsawg leeg, khoom, lub hom phiaj thiab cov lus qhia rau kev siv
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Dab tsi yog qhov muaj pes tsawg leeg ntawm nicotinic acid? Tom qab tag nrho, nws yog ib qho tshuaj vitamin thiab tshuaj uas koom nrog hauv feem ntau cov tshuaj tiv thaiv oxidative ntawm lub cev hlwb. Nws tseem hu ua niacin, vitamin PP, vitamin B3, thiab qee zaum B5. Nws yog ib qho tsim nyog rau ib tus neeg txhua hnub ntawm 15 mus rau 20 mg ib hnub.

Qhov xav tau txhua hnub ntawm cov vitamin no tuaj yeem ua tiav los ntawm cov khoom noj, cov vitamins, nrog rau ampoules rau kev txhaj tshuaj intramuscular. Txawm li cas los xij, ua ntej ua kom tsis muaj niacin hauv lub cev, koj yuav tsum nkag siab txog nws cov txiaj ntsig zoo, nrog rau kawm cov lus qhia rau kev siv cov ntaub ntawv nrov tshaj plaws thiab zoo ntawm cov vitamin.

Kev sib xyaw thiab tshuaj muaj txiaj ntsig

Vitamin PP feem ntau yog cov kws kho mob sau. Nws yog tsim nyob rau hauv daim ntawv ntawm cov tshuaj nyob rau hauv ampoules thiab ntsiav tshuaj. Cov muaj pes tsawg leeg ntawm nicotinic acid yog txaus siab rau ntau yam. Yog li ntawd, peb piav qhia tias nws suav nrog cov vitamin nws tus kheej. Ntxiv nrog rau cov piam thaj thiab stearic acid. Cov tshuaj muag hauv ampoules uas tsis yog nicotinic acidmuaj dej kho thiab sodium bicarbonate.

Raws li cov tshuaj pharmacological ntawm nicotinic acid, nws muaj hypolipidemic, vasodilating, antipellagric thiab hypocholesterolemic nyhuv ntawm lub cev. Kev noj txaus ntawm cov vitamin no normalizes tus mob ntawm cov ntaub so ntswg, tswj kev puas tsuaj ntawm glycogen, synthesis ntawm proteins, carbohydrates thiab rog. Cov muaj pes tsawg leeg ntawm nicotinic acid pab nws inhibit lipolysis, txo qis qib ntawm triglycerides thiab cov roj cholesterol hauv cov ntshav. Nws kuj tseem paub txog nws cov tshuaj tiv thaiv atherogenic thiab detoxifying zog. Kev siv cov vitamin PP pab nthuav cov hlab ntsha, txhim kho microcirculation, thiab txo cov ntshav txhaws.

tso tawm daim ntawv ntawm nicotinic acid
tso tawm daim ntawv ntawm nicotinic acid

Cov lus qhia rau kev siv

Cov muaj pes tsawg leeg ntawm nicotinic acid ampoules tso cai rau lawv siv los kuaj pom pellagra tshwm sim los ntawm qhov tsis muaj vitamin hauv lub cev. Cov ntsiav tshuaj thiab cov kev daws teeb meem nrog nws cov ntsiab lus tau qhia nyob rau hauv txoj kev kho mob raws li hauv qab no:

  1. Ischemic circulatory disorders hauv hlwb ua haujlwm.
  2. Spasm ntawm cov hlab ntsha hauv caj dab.
  3. Dyslipidemia.
  4. Spasm ntawm lub raum hlab ntsha.
  5. Nyob ntev kho qhov txhab ntawm daim tawv nqaij.
  6. Cov teeb meem tshwm sim los ntawm ntshav qab zib mellitus (nrog rau ntshav qab zib polyneuropathy, microangiopathy).
  7. YHypoacid gastritis, enterocolitis, colitis.
  8. Malabsorption Syndrome.
  9. Tus mob siab thiab mob ntev thiab lwm yam kab mob siab.
  10. Neuritis ntawm lub ntsej muag paj hlwb.
  11. Dermatosis.
  12. Kev poob phaus.
  13. Kev tsis txaus noj haus.
  14. malignant qog.
  15. YHyperthyroidism.
  16. Gastrectomy.
  17. Nrog kev qaug cawv ntawm ntau lub hauv paus chiv keeb: cawv, tshuaj, tshuaj.

Niacin belongs rau qeb ntawm cov tshuaj uas xav tau kev qhia kho mob ua ntej siv. Tsuas yog tus kws kho mob tshwj xeeb tuaj yeem txiav txim siab qhov xav tau ntawm kev siv cov tshuaj no, nrog rau kos nws cov tshuaj pes tsawg.

nicotinic acid deficiency
nicotinic acid deficiency

Kev txhaj tshuaj. Cov yam ntxwv ntawm cov txheej txheem

Cov koob tshuaj nicotinic acid yog txiav txim siab raws li qhov xwm txheej ntawm lub cev. Tsis tas li ntawd, nyob ntawm nws, txoj kev tswj hwm ntawm cov tshuaj raug xaiv. Nrog rau cov kab mob xws li pellagra, cov tshuaj yuav tsum tau txhaj rau hauv cov hlab ntsha. Qhov tsis txaus ntawm cov vitamin PP kuj tuaj yeem raug them los ntawm kev txhaj tshuaj intramuscular ntawm nicotinic acid.

Cov lus qhia rau cov tshuaj muaj cov ntaub ntawv hais tias thaum lub sij hawm kho pellagric, cov tshuaj yuav tsum tau muab intramuscularly 1-2 zaug ib hnub twg, 100 mg lossis 50 mg rau hauv cov hlab ntsha. Yog li ntawd, kev kho mob yuav tsum txuas ntxiv rau 10 mus rau 15 hnub. Hauv ib qho xwm txheej tom qab mob stroke ischemic, cov tshuaj yuav tsum tau muab rau hauv qhov ntau ntawm 50 mg.

Koj yuav tsum tau txhaj tshuaj raws li qee txoj cai. Yog tias xav tau kev tswj hwm intramuscular, 1 ml ntawm 1% niacin tov hauv ampoules yuav xav tau. Rau kev txhaj tshuaj rau hauv cov hlab ntsha, los ntawm 1 mus rau 5 ml ntawm cov tshuaj 1% yog yuav tsum tau, yav tas los diluted nyob rau hauv ib tug tshwj xeeb physiological tov nrog ib tug ntim ntawm 5 ml.

Kev siv cov nicotineacid intramuscularly lossis subcutaneously yog nrog los ntawm kev tsis txaus siab thiab mob. Ob peb feeb tom qab txhaj tshuaj, qhov kub hnyiab yuav tshwm sim, uas tom qab ntawd dhau mus. Kev txhaj tshuaj rau hauv cov hlab ntsha tuaj yeem ua rau muaj qhov kub thiab txias ntawm daim tawv nqaij. Xws li cov tshuaj tiv thaiv yog lub cev ib txwm teb rau cov tshuaj vitamin PP. Yog tias tsis muaj qhov liab liab, qhov no yuav qhia tau tias ua txhaum ntawm cov ntshav. Yog tias qhov mob thiab kub hnyiab tom qab txhaj tshuaj ntev dua 30 feeb, ces qhov kev txhaj tshuaj tsis tau ua kom raug. Txhawm rau tshem tawm cov xwm txheej zoo li no, nws yog qhov yuav tsum tau siv cov kev pabcuam ntawm tus kws saib xyuas neeg mob thiab ua cov kev txhaj tshuaj hauv tus kws kho mob lub chaw haujlwm.

nicotinic acid txhaj tshuaj
nicotinic acid txhaj tshuaj

Cov lus qhia rau kev siv cov ntsiav tshuaj

Tshuaj nyob rau hauv daim ntawv ntawm nicotinic acid ntsiav tshuaj yuav tsum tau noj tsuas yog tom qab noj mov. Koj tsis tuaj yeem ua nws ntawm lub plab khoob lossis tam sim ntawd tom qab sawv. Cov koob tshuaj prophylactic ntawm cov tshuaj yog nyob ntawm qhov xwm txheej ntawm lub cev thiab hnub nyoog. Raws li cov lus qhia rau kev siv cov nicotinic acid nyob rau hauv cov ntsiav tshuaj, cov me nyuam yuav muab tau los ntawm 5 mus rau 25 mg ntawm vitamin PP, thiab cov neeg laus - los ntawm 12 mus rau 25 mg. Nrog rau qhov tsis txaus ntawm niacin, nrog rau cov kab mob xws li pellagra, cov neeg laus tau pom tias muaj ntau npaum li cas ntawm 100 mg ntawm cov tshuaj 2 mus rau 4 zaug hauv ib hnub. Cov menyuam yaus tuaj yeem muab tau los ntawm 12 mus rau 50 mg ntawm cov tshuaj hauv ntsiav tshuaj 2 lossis 3 zaug hauv ib hnub. Kev kho mob hauv qhov no yog los ntawm 14 txog 21 hnub.

Thaum txiav txim siab qhov mob atherosclerotic vascular, qhov pom zoo noj yog los ntawm 2 mus rau 3 g ntawm cov tshuaj, muab faib ua 2-4 koob tshuaj ib hnub. Kev kho mob ntawm dyslipidemia yog nqa tawm los ntawm ib txoj kev siv ib zaug50 mg ntawm cov tshuaj ib hnub twg. Thaum tsis muaj kev phiv los ntawm cov tshuaj nicotinic acid, qhov koob tshuaj no tuaj yeem nce ntxiv los ntawm ib mus rau 2-3 koob tshuaj ib hnub. Yam tsawg kawg ntawm kev kho mob kav 30 hnub. Kev kho rov qab tuaj yeem ua tau tom qab kuaj los ntawm tus kws kho mob, dhau qhov kev sim los txiav txim siab cov niacin, nrog rau lub sijhawm ncua tom qab 1 lub hlis ntawm kev siv cov ntsiav tshuaj.

Hauv lwm qhov xwm txheej uas yuav tsum tau muaj vitamin PP, qhov koob tshuaj ntawm cov tshuaj no yuav tsum tau ua raws li 5-25 mg ib hnub rau menyuam yaus thiab 20-50 mg rau cov neeg laus. Raws li cov lus qhia rau kev siv cov nicotinic acid hauv cov ntsiav tshuaj, qee zaum, cov neeg laus yuav raug muab 100 mg ntawm cov tshuaj, muab faib ua ob peb koob tshuaj ib hnub. Nws yuav tsum tau noj tom qab noj mov xwb.

Cov lus qhia rau kev siv nicotinic acid
Cov lus qhia rau kev siv nicotinic acid

Ntau dhau thiab phiv

Cov muaj pes tsawg leeg ntawm nicotinic acid tuaj yeem ua rau kev loj hlob ntawm kev tsis haum tshuaj lossis kev phiv. Tshwj xeeb tshaj yog tias koj siv cov tshuaj, tsis quav ntsej cov lus qhia. Hauv cov xwm txheej zoo li no, kev siv cov ntsiav tshuaj lossis tshuaj txhaj tshuaj tuaj yeem ua rau muaj kev phiv hauv qab no:

  1. Hypotension.
  2. Liab ntawm daim tawv nqaij (lub ntsej muag thiab lub cev sab sauv).
  3. Tingling nrog rau qhov kub hnyiab uas tsis ploj mus ntev.
  4. kiv taub hau thiab mob taub hau.
  5. Kev ua kua txiv plab.
  6. Orthostatic hypotension tuaj yeem txhim kho yog tias cov tshuaj tso rau hauv cov tshuaj tsis raug.
  7. Ntshai maj ntshav mus rau lub taub hau thiab daim tawv nqaij ntawm lub ntsej muag.
  8. khaus khaus lossis khaus khaus.
  9. Dyspepsia.
  10. Mob thiab o hauv thaj tsam ntawm subcutaneous lossis intramuscular tswj hwm ntawm cov tshuaj.
  11. Hypophosphatemia.
  12. Txo cov platelet suav.
  13. Insomnia, myalgia.
  14. Txhawj xeeb.
  15. Kev tsis pom kev thiab qhov o ntawm daim tawv muag.
  16. YExfoliative dermatitis.

Yog tias koj noj niacin ntawm ntau npaum li qhov pom zoo, cov kab mob xws li anorexia, ntuav, raws plab, plab zom mov, siab tsis ua haujlwm, rog rog, arrhythmia, hyperglycemia, paresthesia, gastric ulcer tuaj yeem tsim. Kev ua haujlwm ntawm alkaline phosphatase tuaj yeem tshwm sim.

Kev noj ntau dhau ntawm nicotinic acid yog qhov txaus ntshai rau qhov tshwm sim ntawm cov rog degeneration ntawm daim siab. Txhawm rau kom tsis txhob ua rau muaj qhov sib txawv, thaum kho cov vitamin PP, koj yuav tsum tau saib xyuas kev noj haus. Cov kws kho mob pom zoo kom noj zaub mov kom ntau li ntau tau nrog cov amino acids thiab methionine. Txhawm rau tshem tawm cov tsos mob ntawm kev noj tshuaj ntau dhau, cov tshuaj prolipotropic yuav raug sau.

overdose ntawm nicotinic acid
overdose ntawm nicotinic acid

Contraindications rau kev siv

Ua ntej pib kev kho mob, yuav tsum mus ntsib kws kho mob. Tsis yog txhua tus tuaj yeem noj cov tshuaj vitamin no hauv daim ntawv ntawm cov ntsiav tshuaj lossis txhaj tshuaj nicotinic acid intramuscularly. Cov lus qhia rau kev siv muaj cov ntaub ntawv hais txog cov kev mob tshwm sim uas yuav tshwm sim thaum noj tus kheej. Contraindications suav nrog cov xwm txheej hauv qab no:

  1. Ib leeg intoleranceCheebtsam ntawm cov tshuaj.
  2. YPeptic ulcer ntawm lub plab thiab duodenum.
  3. mob ntshav siab.
  4. Kev mob raum tsis ua haujlwm.
  5. Gout.
  6. Ntawm no myocardial infarction.
  7. Kev cev xeeb tub.
  8. Ntsuag mis.
  9. Niacin yuav tsum tsis txhob noj los ntawm cov menyuam yaus hnub nyoog qis dua 15.

Nws yog txwv tsis pub siv cov tshuaj no thaum los ntshav thiab ntshav, nrog rau lub siab ua haujlwm tsis zoo. Nws kuj tseem yuav tsum tau coj mus rau hauv tus account qhov ua tsis taus ntawm lub cev rau nicotinic acid. Ib qho ntxiv contraindication yog exacerbation ntawm gastric ulcers thiab hyperuricemia.

txhaj tshuaj intramuscular
txhaj tshuaj intramuscular

cov lus qhia tshwj xeeb rau kev siv

Thaum npaj rau kev kho mob nrog nicotinic acid, nws yuav tsum nco ntsoov tias kev txhaj tshuaj yog qhov mob heev, thiab yog li ntawd tsis haum rau cov neeg uas muaj qhov mob tsawg. Ntxiv nrog rau nws cov txiaj ntsig, vitamin PP kuj tseem pab tshem tawm cov tshuaj lom thiab cov hlau hnyav los ntawm lub cev. Yog li ntawd, cov neeg uas haus cawv thiab haus luam yeeb ib ntus raug txhaj tshuaj nicotinic acid intramuscularly rau kev tiv thaiv. Cov lus qhia rau kev siv hais tias nyob rau hauv cov xwm txheej zoo li no, kev noj 1 g ntawm cov tshuaj nquag hauv ib hnub raug pom zoo.

Thaum lub sijhawm kho, yuav tsum tau saib xyuas lub siab. Tshwj xeeb tshaj yog thaum siv loj npaum li cas ntawm cov tshuaj. Koj yuav tsum tau coj mus rau hauv tus account qhov tseeb hais tias niacin muaj peev xwm ua rau cov mucous daim nyias nyias. Tias yog vim li cas nws tsis tuaj yeem noj nrog ulcerative lesions ntawm lub plab thiabduodenum. Yog tias cov tshuaj tseem tsim nyog, kev kho mob yuav tsum muaj qhov tsawg kawg nkaus ntawm cov tshuaj, thiab nws tuaj yeem nqa tau tsuas yog thaum lub sijhawm tshem tawm tus kab mob.

Txhawm rau txo qhov ua kom khaus khaus ntawm plab hnyuv, cov ntsiav tshuaj nicotinic acid yuav tsum tau noj nrog mis. Txhawm rau tiv thaiv hepatotoxicity, nws yog ib qho tsim nyog yuav tsum ua kom cov zaub mov muaj txiaj ntsig zoo thaum kho nrog cov khoom noj uas muaj methionine. Qhov no yog, ua ntej ntawm tag nrho cov, buckwheat, khoom noj siv mis, ntses thiab txhua yam legumes. Tsis tas li, tus kws kho mob yuav pom zoo kom ua ke ntawm nicotinic acid nrog lipotropic tshuaj.

ampoule nrog nicotinic acid
ampoule nrog nicotinic acid

Nicotinic acid hauv kev npaj

Vitamin PP tau dav siv tsis yog rau kev kho mob nkaus xwb. Rau lub sijhawm ntev heev, nicotinic acid tau nrov heev hauv cosmetology. Nws yog siv los ua ib txoj hauv kev rau kev poob phaus thiab kev loj hlob ntawm cov plaub hau, nrog rau kev txhim kho ntawm daim tawv nqaij ntawm lub ntsej muag. Ntxiv nrog rau cov ntsiav tshuaj nicotinic acid, koj tuaj yeem noj multivitamin complexes nrog nws cov ntsiab lus. Lawv yuav ua rau lub cev muaj txiaj ntsig zoo li cov tshuaj, tab sis tib lub sijhawm lawv yuav pab tsim kom tsis muaj lwm yam khoom muaj txiaj ntsig.

Vitamins nrog nicotinic acid nyob rau hauv muaj pes tsawg leeg yuav tsum tau xaiv tom qab sab laj kws kho mob. Koj kuj yuav tsum tau ua cov kev ntsuam xyuas uas qhia qhov tsis muaj cov as-ham hauv lub cev. Cov khoom noj uas muaj roj ntsha hauv qab no yog suav tias yog cov tshuaj nrov tshaj plaws:

  1. Perfect.
  2. "Supradin".
  3. "Ntxhais ntawv".
  4. Vitrum.
  5. Evalar.

Tag nrho cov ntawm lawv tsis tsuas yog cov vitamins thiab minerals tseem ceeb tshaj plaws rau lub cev, tab sis kuj muaj nicotinic acid.

Vitamin PP thiab poob phaus

Lub peev xwm ntawm nicotinic acid los cuam tshuam cov phaus ntxiv yog vim nws cov khoom tshwj xeeb. Vitamin PP muaj peev xwm oxidize carbohydrates thiab cov rog uas tau nkag mus rau hauv lub cev nrog zaub mov. Nws yog nrog qhov tsis muaj nicotinic acid uas ntau qhov kev xav tau ntau ntxiv rau cov khoom qab zib. Kev sib ntaus tawm tsam qhov hnyav tshaj yog vim muaj cov khoom nram qab no uas cov tshuaj no muaj:

  1. Normalization ntawm metabolism.
  2. Txo cov roj cholesterol.
  3. Kev sib xyaw ntawm cov tshuaj nicotinic acid txhawb lub plab zom mov.
  4. Kev tawm ntawm lub cev ntawm cov tshuaj lom thiab impurities uas tso rau ntawm phab ntsa ntawm lub plab thiab cuam tshuam cov txheej txheem ntawm kev zom zaub mov.

Txawm tias muaj txiaj ntsig zoo ntawm cov vitamin rau daim duab, nws yuav tsum nco ntsoov tias cov txiaj ntsig zoo ntawm kev siv yuav tuaj tsuas yog tias koj muab cov chav kawm nrog kev noj haus thiab kev ua kis las. Koj yuav tsum tau coj mus rau hauv tus account qhov tseeb tias ntau npaum li cas ntawm nicotinic acid nyob rau hauv cov kev npaj yuav tsum tsis txhob ntau tshaj li ntawm 1 g.

nicotinic acid ntsiav tshuaj
nicotinic acid ntsiav tshuaj

Nicotinic acid deficiency

Nrog tsis muaj nicotinic acid, ntau yam txheej txheem pathological tuaj yeem txhim kho. Ib qho txaus ntshai tshaj plaws yog kab mob hu ua pellagra. Cov kab mob hauv qab no feem ntau nkag siab rau qhov tsis muaj vitamin PP:

  1. Vessels.
  2. Leather.
  3. Npaj.

Koj tuaj yeem txheeb xyuas qhov tsis txaus ntawm nicotinic acid los ntawm cov tsos mob hauv qab no:

  1. Cov ntsiab lus tshwm sim ntawm daim tawv nqaij, uas zoo li kub hnyiab los ntawm lub hnub rays. Nrog rau lub hnub raug lub hnub ntev, cov pob no pib nce, darken thiab tev tawm.
  2. Kev ua haujlwm ntawm plab hnyuv yog cuam tshuam, uas yog nrog xeev siab, ntuav thiab lwm yam tsos mob tsis zoo nyob rau hauv daim ntawv ntawm raws plab. Hauv qhov mob hnyav tshaj plaws, los ntshav yuav tshwm sim.
  3. Mob nkees thiab insomnia tshwm sim. Tus mob no tuaj yeem ua rau muaj kev nyuaj siab, mob hlwb, thiab txawm tias hnov qab.
  4. Nrog tsis muaj vitamin PP, cov mucous membranes feem ntau ua o thiab redden.

Qhov laj thawj tseem ceeb rau kev loj hlob ntawm pellagra yog kev noj cov nicotinic acid tsis txaus, nrog rau nws qhov tsis muaj nyob hauv kev noj haus.

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