Hormonal therapy yog ib txoj hauv kev kho ntau yam pathologies, txij li cov tshuaj hormones yog cov protein sib txuas uas tuaj yeem cuam tshuam rau ntau yam pathogenetic mechanisms uas txhim kho hauv tib neeg lub cev.
Kev kho tshuaj hormone feem ntau yog siv los kho cov qog nqaij hlav hauv lub mis zoo. Txoj kev kho no tseem hu ua antiestrogen, vim nws yog tsom rau kev tiv thaiv qhov tsis zoo ntawm cov tshuaj estrogen ntawm cov qog hlwb.
Tamoxifen thiab aromatase inhibitors yog cov tshuaj feem ntau tau sau tseg rau mob qog noj ntshav.
Nws tsim nyog sau cia tias kev kho tshuaj hormone yog tus yam ntxwv los ntawm kev ua haujlwm ntawm lub cev, yog li nws tuaj yeem siv los rhuav tshem cov qog nqaij hlav cancer tom qab kev kho hluav taws xob lossis kev phais, nrog rau tom qab noj tshuaj khomob kom txo tau txoj kev pheej hmoo ntawm rov tshwm sim dua. ntawm tus kab mob.
Cov tshuaj rau kev kho tshuaj hormone yog:
- muaj feem yuav mob qog noj ntshav siab;
- recurrence in non-invasive mis cancer;
- mob qog noj ntshav thaum xav tautxo qog loj rau lwm yam kev kho mob;
- metastatic qog.
Kev kho tshuaj hormone rau cov kab mob no yog txhawm rau thaiv lossis rhuav tshem cov tshuaj estrogen-sensitive receptors, nrog rau txo cov concentration ntawm cov tshuaj no hauv cov ntshav.
Hormone replacement therapy for women is also very common, which is taken to eliminate menopausal disorders. Qhov kev kho no yog qhov sib txawv ntawm cov qauv kev kho tshuaj hormones, vim nws yog tsom rau kev rov ua kom lawv qhov tsis txaus hauv lub cev, thiab tsis cuam tshuam rau lawv.
Kev Kho Mob Hloov Kho yog ua raws li kev siv ntau yam tshuaj hormones kev sib deev, uas tshem tawm cov tsos mob ntawm zes qe menyuam tsis ua haujlwm, xws li kub flashes thiab tawm hws ntau dhau, mob taub hau, chim siab thiab tsis nco qab vim qhov tsis txaus ntawm cov tshuaj estrogen.
Yuav ua li cas haus cawv thaum cev xeeb tub, tus kws kho mob yuav tsum txiav txim siab. Feem ntau, cov tshuaj estrogens tsawg tau raug sau ua ke nrog cov tshuaj progestogens, uas tiv thaiv kev txhim kho ntawm cov txheej txheem hyperplastic hauv endometrium. Nyob rau tib lub sijhawm, xws li kev kho hormonal yuav tsum tau ua tsawg kawg 5-7 xyoo, uas pab tiv thaiv kev txhim kho pob txha thiab myocardial infarction ntawm cov poj niam postmenopausal.
Kuv yuav tsum hais tias kev kho tshuaj hormone yog ua tsis tau tsuas yog ntawm cov poj niam, tab sis kuj ntawm cov txiv neej uas muajkuaj mob qog noj ntshav prostate. Hauv qhov no, kev kho antiandrogen yog ua, uas pab thaiv kev loj hlob, kev loj hlob, thiab kev loj hlob ntawm cov qog nqaij hlav cancer.
Nyob rau hauv kev kho mob, androgen blockades yog siv, uas yog nqa tawm los ntawm kev kho mob castration los yog los ntawm kev sau tshuaj antiandrogens. Cov tshuaj estrogen feem ntau siv, uas inhibit qhov tso tawm ntawm LHRH, txo qis kev ua haujlwm ntawm Leydig hlwb, thiab tseem ua rau cytotoxically ntawm prostate adenocarcinoma cells.
