Kev kho tshuaj tua kab mob tau ntev tau tshwm sim hauv peb lub ntiaj teb niaj hnub no. Nws yog qhov nyuaj rau xav txog yuav ua li cas peb cov poj koob yawm txwv tswj tsis tau cov tshuaj no, vim tias ntau cov kab mob thiab cov kab mob, nkag mus rau hauv tib neeg lub cev, tuaj yeem ua rau mob hnyav. Qee zaum lawv kuj ua rau tuag. Tias yog vim li cas nws thiaj li yuav tsum tau sab laj nrog kws kho mob hauv lub sijhawm thiab haus cov tshuaj uas nws tau sau tseg, suav nrog tshuaj tua kab mob. Txog rau tam sim no, lawv tau dav tsim los ntawm cov tuam txhab tshuaj. Cov tshuaj tua kab mob hauv kev txhaj tshuaj yog suav tias yog qhov zoo tshaj plaws. Lawv pib ua sai sai thiab tsis ua rau lub plab zom mov. Cov tshuaj "Amikacin" (RLS) belongs rau ib pab pawg neeg ntawm cov tshuaj tua kab mob uas qhia rau siv txawm nyob rau hauv cov me nyuam. Vim li no, nws yog dav sau los ntawm kws kho mob thiab kws kho mob. Peb yuav piav qhia ntxaws txog cov tshuaj tua kab mob ntawm pawg aminoglycoside thiab tham txogNws indications thiab contraindications.
piav qhia luv ntawm cov khoom siv tshuaj
Ua ntej me ntsis, peb twb tau qhia meej tias Amikacin yog cov tshuaj tua kab mob ntawm pawg aminoglycoside. Cov tshuaj suav hais tias yog semi-synthetic, uas txhais tau tias nws ua rau muaj kev phiv me me.
Qhov nrov ntawm cov cuab yeej no tau muab los ntawm nws cov khoom. Qhov tseem ceeb tshaj plaws yog kev hloov pauv qeeb ntawm cov kab mob thiab cov kab mob mus rau cov khoom tseem ceeb. Txawm tias tom qab kev kho mob ntau zaus nrog tus neeg sawv cev no, cov kab mob tsis muaj sijhawm los txhim kho nws.
Thaum "Amicacin" nkag rau hauv lub cev, nws nkag mus rau hauv cov cell membrane sai sai. Cov tshuaj nquag cuam tshuam nrog cov kab mob protein. Yog li ntawd, nws cov synthesis cuam tshuam. Tom qab qee lub sijhawm, cov kab mob tuag, thiab qhov no feem ntau tshwm sim hauv ib lossis ob hnub ntawm kev kho.
Txoj kev tshuaj
Tom qab txhaj tshuaj Amikacin, nws nkag mus rau hauv tag nrho cov ntaub so ntswg ntawm lub cev. Yog tias koj tau muab cov tshuaj tso rau hauv txoj hlab ntshav, ces nws qhov siab tshaj plaws concentration yuav mus txog hauv peb caug feeb. Nrog kev txhaj tshuaj intramuscular, cov nyhuv tib yam yuav tuaj tom qab ib teev xwb.
Kwv yees li kaum ob teev cov txiaj ntsig ntawm cov tshuaj siv tau ntev. Tom qab lub sijhawm no, kev txhaj tshuaj "Amikacin" yuav tsum tau rov ua dua. Nws yog noteworthy tias cov metabolism hauv cov tshuaj nyob rau hauv lub cev tsis tshwm sim. Nws raug tshem tawm hauv daim ntawv hloov me ntsis los ntawm ob lub raum hauv txhua pawg ntawm cov neeg mob. Hauv cov neeg laus, cov txheej txheem no yuav siv li plaub teev. Tab sis rau cov menyuam mos, txhua yam tshwm sim qeeb dua - txog li yim teev. Yog vim li casNws tsis yog qhov xav tsis thoob tias hauv cov neeg mob uas muaj keeb kwm ntawm lub raum, cov txheej txheem tshem tawm yuav siv sijhawm txog li ib puas teev hauv qee kis.
Qhov kev ua ntawm "Amicin" txuas mus rau cov kab mob gram-negative thiab gram-positive. Yog tias peb xav txog qhov teeb meem no me ntsis ntxiv, peb tuaj yeem hais tias cov tshuaj tua kab mob tiv thaiv tau zoo heev nrog cov kab mob hauv qab no:
- E. coli;
- salmonella;
- Pseudomonas aeruginosa;
- pseudomonas;
- shigella thiab lwm yam.
Cov kab mob uas teev tseg yog gram-negative. Cov kab mob Gram-zoo muaj xws li:
- staphylococci;
- streptococci;
- enterococci.
Txawm li cas los xij, nws tsim nyog ntxiv tias cov tshuaj tua kab mob tsis muaj zog heev cuam tshuam nrog ob kab mob kawg. Feem ntau, Amikacin (RLS) yog siv nyob rau hauv cov ntaub ntawv no raws li kev kho mob adjuvant. Nws tsuas yog ntxiv lwm cov tshuaj.
Nco ntsoov tias Amikacin tsis tiv nrog cov kab mob anaerobic. Yog li, nws tsis raug sau tseg txawm tias muaj kev txhawb nqa los ua ib feem ntawm txoj kev kho mob nyuaj.
Composition
Amikacin (RLS) yog hais txog cov tshuaj uas tsis muaj cov khoom siv ntau. Cov khoom xyaw nquag yog amikacin sulfate. Nws muaj nyob rau hauv txhua hom tshuaj tso tawm thiab ua kom nws cov txiaj ntsig zoo.
Nws tuaj yeem hais tias cov khoom siv ntxiv uas ua kom nkag mus ntawm cov khoom tseem ceeb rau hauvlub cev nqaij daim tawv ua raws li lub tsheb. Cov khoom no suav nrog:
- dej;
- sodium disulfate;
- sodium citrate.
Txhua yam tshuaj uas tau teev tseg yog muaj kev nyab xeeb rau tib neeg thiab tsis tshua muaj kev tsis haum tshuaj.
Kev tso tawm thiab ntau npaum li cas
Cov tshuaj yog tsim los ntawm cov chaw tsim khoom tsuas yog ob hom: hmoov thiab tshuaj. Los ntawm cov hmoov, koj tuaj yeem npaj cov tshuaj "Amikacin". Kev txhaj tshuaj hauv qhov no yog ua tom qab diluting cov ntsiab lus ntawm lub vial nrog Novocaine lossis Lidocaine. Feem ntau hom tshuaj no yog ntim rau hauv lub khob iav. Lawv qhov ntim tsis tshaj kaum milliliters. Tus nqi nruab nrab ntawm ib lub raj mis yog li ntawm tsib caug rubles.
nquag sau Amikacin hauv ampoules los ntawm kws kho mob. Lawv muaj cov tshuaj npaj ua tiav uas tsis tas yuav diluted nrog txhua yam. Ampoules tuaj yeem muag hauv ntim ntawm ob thiab plaub milliliters. Lawv tus nqi nruab nrab tsis tshaj ib puas rubles. Cov pob ntawv thawv muaj tsib lossis kaum ampoules ntawm cov tshuaj tua kab mob.
Yog tias peb tham txog cov tshuaj Amikacin (RLS), koj yuav tsum paub tias hauv ib milliliter ntawm cov tshuaj muaj ob puas thiab tsib caug milligrams ntawm cov tshuaj nquag. Txhua lub vial ntawm cov tshuaj tua kab mob muaj ib gram ntawm cov khoom xyaw nquag
Cov lus qhia rau kev siv "Amicacin"
Kev siv tshuaj yeeb yog dav heev. Ua ntej ntawm tag nrho cov, nws yog sau nyob rau hauv cov ntaub ntawv ntawm nrhiav tau ntawm kis kab mob thiab inflammatory kab mob. Lawv raug kho zoo nrog cov tshuaj txawm tiasnyob rau hauv cov mob hnyav tshaj plaws.
Cov npe qhia rau kev siv "Amicacin" suav nrog kev kis kab mob tom qab kev phais. Cov xwm txheej zoo li no feem ntau tshwm sim hauv cov tshuaj thiab ua rau tus neeg mob rov zoo li qub.
Sepsis kuj tuaj yeem kho nrog cov tshuaj tua kab mob no. Qhov no tau qhia hauv nws cov lus qhia rau kev siv, tab sis kev kho mob feem ntau yog ua los ntawm kws kho mob. Ua rau koj tus kheej, tshwj xeeb tshaj yog thaum muaj xwm txheej hnyav, yog txwv tsis pub.
Nyob rau hauv kis kab mob ntawm lub ntsws thiab bronchi, tus kws kho mob zoo li yuav muab cov tshuaj no. Nws yuav pab nrog mob ntsws, mob ntsws thiab lwm yam kab mob.
"Amikacin" yog qhov zoo heev los daws cov mob hnyav xws li peritonitis. Tsis tas li ntawd, kev kho mob nrog cov tshuaj tua kab mob no tau muab rau yuav luag txhua qhov kev kis kab mob hauv plab.
Kab mob ntawm cov kab mob genitourinary kuj tau txais txiaj ntsig rau "Amicacin". Kev kho mob ntawm cov kab mob no (thiab peb tab tom tham txog cystitis, urethritis, pyelonephritis thiab lwm yam teeb meem) feem ntau yog ntev thiab nrog ntau cov tsos mob tsis zoo.
Cov lus qhia rau kev siv qhia ntau yam kab mob ntxiv uas yuav tsum tau kho nrog cov tshuaj peb piav qhia. Cov no muaj xws li kab mob ntawm lub biliary ib ntsuj av, paj hlwb thiab daim tawv nqaij. Ntawm cov kab mob hnyav tshaj plaws, mob meningitis thiab kab mob purulent ntawm daim tawv nqaij tuaj yeem paub qhov txawv.
Leej twg yuav tsum tsis txhob muab Amikacin?
Cov tshuaj tua kab mob hauv kev txhaj tshuaj no muaj cov npe me me ntawm contraindications, uas yog qhov xav tsis thoob rau cov tshuaj uas koom nrog cov pab pawg. Yog vim li casNws yog dav sau ntawv, tab sis nws tseem tsim nyog kawm contraindications thiaj li tsis ua mob rau koj noj qab haus huv.
Tau kawg, koj yuav tsum tsis txhob siv tshuaj yog tias koj ua xua rau nws cov khoom. Tsis tas li ntawd, koj yuav tsum tsis kam txais kev kho mob thaum muaj teeb meem raum loj. Cov kab mob no ua rau nws nyuaj rau tshem tawm cov tshuaj ntawm lub cev, uas ua rau nws tsub zuj zuj thiab intoxication.
Rau cov niam uas muaj menyuam, yuav tsum tsis txhob muab tshuaj rau txhua qhov xwm txheej. Thaum pub niam mis, "Amikacin" kuj tsis qhia.
Muaj teeb meem uas cov kws kho mob tau sau tshuaj rau cov menyuam mos (piv txwv li, kev kho mob sepsis). Txawm li cas los xij, cov me nyuam ntxov ntxov yuav tsum tsis txhob txhaj tshuaj tua kab mob. Tsuas yog nyob rau lub sijhawm uas tus menyuam mos lub neej raug hem, tus kws kho mob tuaj yeem txiav txim siab txog kev kho mob nrog Amikacin.
Nyob rau hauv tus neeg mob uas muaj mob neuritis ntawm lub ntsej muag paj hlwb, cov tshuaj tau muab tshuaj nrog kev saib xyuas zoo. Yog tias ua tau, tus kws kho mob yuav tsis kam kho qhov kev pheej hmoo zoo li no. Tab sis nyob rau qee qhov xwm txheej, nws tseem tuaj yeem ua tau.
Qee nuances of treatment
Kev txiav txim los ntawm cov lus qhia rau kev siv, Amikacin yog qhov tsim nyog rau kev txhaj tshuaj intramuscular, tso dej, tso dej thiab dav hlau. Txoj kev los ntawm cov npe no tsuas yog xaiv los ntawm tus kws kho mob tuaj koom. Nws los ntawm txhua qhov qhia thiab qhov hnyav ntawm tus kab mob.
Nyob rau hauv kev kho mob, tus neeg mob yuav tsum tau kuaj xyuas txhua lub lim tiam txhawm rau saib xyuas lub raum. Tsis tas li ntawd, yuav tsum tau them nyiaj tshwj xeeb rau qhov kev kuaj hnov lus. Nws sharpness tuaj yeemmus down. Qhov no yog qhov tseeb tshwj xeeb hauv kev kho cov menyuam yaus. Yog tias muaj teeb meem zoo li no, cov tshuaj tua kab mob yuav tsum raug txiav tawm.
Cov kws kho mob uas kuaj cov kab mob sib kis hauv cov neeg mob tau sau cov tshuaj hauv daim ntawv ntawm infusions. Qhov no tuaj yeem ua rau hauv cov hlab ntsha los ntawm lub syringe lossis drip. Hauv thawj qhov kev xaiv, qhov kev taw qhia yuav tsum qeeb, thiab hauv qhov thib ob - tsis pub dhau rau caum feeb.
Tsis tas li, koj tuaj yeem nkag mus rau cov tshuaj thiab intramuscularly. Feem ntau, daim ntawv hmoov yog siv rau cov hom phiaj no, tab sis nws yog tov nrog saline. Nws yuav tsum tau nco ntsoov tias kev txhaj tshuaj ntawm cov tshuaj tua kab mob ua rau mob. Yog txhaj tshuaj sai sai, nws yuav tsis yaj, ua rau muaj qhov tsis xis nyob.
Tshuaj ntau ntau
Rau txhua lub hnub nyoog, tus kws kho mob tuaj koom yuav xaiv cov tshuaj raws li kev sib xyaw ua ke. Txawm li cas los xij, txhua tus kws tshaj lij tseem ua raws li cov lus pom zoo.
Thaum kuaj pom muaj kab mob hauv cov menyuam mos tshiab, nws yuav tsum suav cov tshuaj raws li tus menyuam lub cev hnyav: kaum milligrams tshuaj tua kab mob rau txhua kilogram. Qhov koob tshuaj no yog khaws cia thaum thawj hnub ntawm kev kho mob. Tom qab ntawd koj yuav tsum rov xam cov koob tshuaj: xya thiab ib nrab milligrams ib kilogram ntawm tus menyuam qhov hnyav. Feem ntau, cov menyuam tau txhaj ob zaug ib hnub.
Ib koob tshuaj zoo sib xws yog muab rau cov menyuam mos txog rau xyoo. Thaum lub hnub nyoog no, lub sijhawm ntawm kaum ob teev ntawm kev txhaj tshuaj yuav tsum tau pom meej meej.
Cov menyuam yaus hnub nyoog 6 txog rau kaum ob xyoos tuaj yeem txhaj tshuaj tom qab yim teev. Tab sis qhov noNws yog ib qho tsim nyog los suav cov tshuaj kom raug, raws li tsib milligrams ib kilogram ntawm qhov hnyav.
Txij thaum muaj hnub nyoog kaum ob, qhov concentration ntawm cov tshuaj nquag hauv lub cev yuav tsum tsis pub tshaj ib thiab ib nrab grams tauj ib hnub. Cov koob tshuaj yog xam raws li hauv qab no: los ntawm tsib mus rau kaum tsib milligrams ntawm cov tshuaj yog noj ib kilogram ntawm tus neeg mob qhov hnyav.
Cov kev kho mob tuaj yeem yog tsib mus rau kaum plaub hnub. Lub sijhawm no feem ntau txaus los daws teebmeem kev noj qab haus huv tag nrho. Txawm li cas los xij, tshwj xeeb tshaj yog mob hnyav, tshuaj tua kab mob tuaj yeem txhaj tau tom qab 6 teev ib ntus. Qhov no yog ua tiav intramuscularly.
Nws yuav tsum tau qhia meej tias yog tias muaj kev xav tau hnyav rau cov neeg mob lub raum tsis txaus, cov tshuaj tuaj yeem siv tau, tab sis raug rau qee yam mob. Ua ntej, qhov ntau npaum li cas yuav tsum raug txo kom tsawg. Qhov thib ob, lub sijhawm nruab nrab ntawm kev txhaj tshuaj yuav tsum tau ua kom tiav. Thib peb, kev taw qhia yuav tsum qeeb heev. Cov neeg laus yuav tsum ua qhov no rau ib teev thiab ib nrab, thiab cov menyuam yaus xav tau ob.
Siv tshuaj rau menyuam yaus
Cov kws kho mob muab tshuaj tua kab mob rau cov menyuam yaus tsis yog txhaj tshuaj lossis intramuscularly. Amikacin tau ua pov thawj tias muaj txiaj ntsig zoo hauv kev kho cov menyuam yaus hauv daim ntawv ntawm inhalations. Nws tau raug pov thawj tias txoj kev no tso cai rau kom ua tiav cov nyhuv yuav luag tam sim ntawm cov tshuaj. Ntxiv mus, nws cov active Cheebtsam tam sim ntawd nkag mus rau hauv lub cev cuam tshuam ntawm lub ua pa system. Txog xya caum feem pua ntawm cov khoom uas tau nkag mus rau hauv lub cev nyob rau ntawm lawv.
Kev nqus pa tau pom zoo kom ua tiav ib thiab ib nrab teev tom qab noj mov. Thaum kawgtus txheej txheem, tus menyuam yuav tsum tsis txhob txav mus rau sab nraud tsawg kawg kaum tsib feeb. Txog li tsib qhov nqus pa tau ua ib hnub. Nrog rau qhov zaus no, rau hnub ntawm kev kho mob txaus. Nws tshwm sim tias qhov tshwm sim tau ua tiav hauv peb hnub.
Kev nqus pa yog npaj los ntawm kev sib xyaw tshuaj tua kab mob thiab dej distilled. Ib qho kev kho mob yuav tsum tau tsib puas milligrams ntawm Amikacin thiab peb milligrams dej.
Muaj kev phiv tshwm sim
Thaum kev kho mob, cov neeg mob tsis tshua muaj kev phiv tshuaj. Feem ntau, txhaj tshuaj tiv thaiv tau zoo los ntawm lub cev. Qhov no siv tau rau cov menyuam mos thiab cov laus. Txawm li cas los xij, qee zaum, cov kev mob tshwm sim tseem tuaj yeem ua tau, thiab tus kws kho mob yuav tsum ceeb toom tus neeg mob txog lawv.
Vim tias cov tshuaj tua kab mob nkag mus rau hauv lub cev los ntawm kev tswj hwm intramuscular thiab intravenous, lub plab zom mov tsis tshua muaj kev txom nyem thaum kho. Tab sis qee tus neeg mob yws yws ntawm xeev siab, ntuav thiab mob siab.
Cov tshuaj tiv thaiv ntawm lub paj hlwb ua rau tus neeg mob muaj teeb meem ntau. Nws ua rau mob taub hau, irritability, nce tsaug zog. Tsis tas li ntawd, tus neeg mob yuav hnov cov ntaub so ntswg thiab tingling nyob rau hauv cov ceg. Qee zaum cov tsos mob no nrog rau cov leeg nqaij twitching. Hauv qhov xwm txheej hnyav tshaj plaws, kev ua pa nres tshwm sim.
Yog tias tus neeg mob muaj qee qhov teeb meem nrog cov kab mob hematopoietic, tom qab ntawd kev kho tshuaj tua kab mob tuaj yeem ua rau muaj ntshav qab zib ntau heev.
Tus neeg mob lub rooj sib hais tshwj xeeb yog cuam tshuam los ntawm Amikacin. Ntxiv mus, nyob rau hauv ib pawg neeg mob, qhov xwm txheej mus txogirreversible theem. Nyob rau tib lub sijhawm, yuav muaj teeb meem nrog kev sib koom tes ntawm kev txav.
Yog tias peb tham txog kev tsis haum tshuaj, lawv tau tshwm sim los ntawm khaus, liab ntawm daim tawv nqaij, o thiab lwm yam tsos mob tsis zoo. Qee zaum muaj kev phiv tshwm sim ntawm qhov chaw txhaj tshuaj. Tus neeg mob hnov mob ntev, uas tuaj yeem hloov mus rau dermatitis. Ua tau phlebitis.
Cov tsos mob ntau dhau
Txhua yam tshuaj, yog siv tsis raug, yuav ua rau muaj kev noj ntau dhau. Qhov no muaj tseeb tshwj xeeb thaum kho nrog tshuaj tua kab mob. Koj tuaj yeem qhia tau tias koj tau noj ntau dhau los ntawm cov tsos mob.
Thaum pib, qhov teeb meem ua rau nws tus kheej muaj kev xeev siab, mob plab, mob taub hau hnyav thiab tsis qab los noj mov. Nyob rau hauv cov ntaub ntawv ntawm Amikacin, qhov no yuav nrog los ntawm tsis hnov lus thiab ua tau convulsions.
Nws pab tsis tau tus neeg mob hauv tsev. Yog tias koj pom cov tsos mob ntawm kev noj tshuaj ntau dhau hauv cov neeg koj hlub, tam sim ntawd hu rau pab pawg kws kho mob lossis coj tus neeg mus rau hauv tsev kho mob koj tus kheej. Nyob rau ntawd nws yuav tau txais hemodialysis. Tsis muaj lwm txoj hauv kev los tshem nws ntawm cov tshuaj tua kab mob ntau dhau hauv lub cev.
Analogues ntawm Amikacin
Qee lub sij hawm tus neeg mob tsis tuaj yeem noj tshuaj tua kab mob rau ib qho laj thawj lossis lwm qhov. Tom qab ntawd analogues tuaj cawm. Amikacin muaj ob peb ntawm lawv, thiab txhua tus ntawm lawv muaj txiaj ntsig zoo thiab tiv thaiv ntau tus kab mob sib kis.
Amikabol thiab Amiksin yog cov kab mob ntau tshaj plaws. Hematsin thiabLycacin.
Cov neeg mob kho nrog Amikacin thov xav tsis thoob los ntawm nws cov txiaj ntsig thiab tus nqi. Ntau tus txawm tsis xav tias nyob rau hnub thib ob ntawm kev kho mob nrog cov tshuaj pheej yig thiab yooj yim lawv yuav pom kev txhim kho hauv lawv tus mob.
Tib lub sijhawm, cov neeg mob feem ntau sau tias lawv tsis pom muaj kev phiv. Lawv tau coj lub neej zoo li qub thiab ua tau zoo.
Feem ntau, cov tshuaj tua kab mob sib cuam tshuam zoo nrog lwm yam tshuaj. Yog li ntawd, cov kws kho mob sau nws ua ib feem ntawm txoj kev kho mob. Qhov kev txwv tsuas yog cuam tshuam nrog diuretics. Lawv txo qis qhov ua tau zoo ntawm Amikacin, uas ua rau muaj kev nce ntxiv hauv cov koob tshuaj txhua hnub rau qhov siab tshaj plaws.
