Ob qho tib si kev tiv thaiv thiab kev kho mob ntawm cov kab mob plawv yuav tsum muaj lub luag haujlwm thiab loj. Cov teeb meem zoo li no tau dhau los ua ntau dua hauv cov neeg niaj hnub no. Yog li ntawd, ntau tus nyiam kho lawv me ntsis maj mam. Cov neeg zoo li no feem ntau tsis quav ntsej txog qhov yuav tsum tau txais kev kho mob, lossis noj tshuaj yam tsis muaj kws kho mob sau ntawv (ntawm cov lus qhia ntawm cov phooj ywg). Txawm li cas los xij, nws tseem ceeb heev uas yuav tsum nco ntsoov tias qhov tseeb tias ib qho tshuaj tau pab lwm tus tsis lav tias nws yuav pab tau koj thiab. Txhawm rau tsim cov txheej txheem kho mob, kev paub txaus thiab kev txawj ntse tsuas yog yuav tsum muaj cov kws tshaj lij. Nws tseem muaj peev xwm sau tau cov tshuaj, tsuas yog siv rau hauv tus account tus yam ntxwv ntawm tus neeg mob lub cev, qhov hnyav ntawm tus kab mob, cov yam ntxwv ntawm nws cov chav kawm thiab anamnesis. Tsis tas li ntawd, niaj hnub no muaj ntau yam tshuaj zoo uas tsuas yog cov kws kho mob tshwj xeeb tuaj yeem xaiv thiab sau ntawv. Piv txwv li, qhov no siv rau sartans - tshwj xeebib pawg tshuaj (lawv kuj hu ua angiotensin 2 receptor blockers). Cov tshuaj no yog dab tsi? Yuav ua li cas angiotensin 2 receptor blockers ua haujlwm? Contraindications rau kev siv cov tshuaj xa mus rau cov pab pawg neeg ntawm cov neeg mob? Nyob rau hauv dab tsi nws yuav tsim nyog siv lawv? Cov tshuaj twg muaj nyob rau hauv pab pawg ntawm cov tshuaj no? Cov lus teb rau tag nrho cov no thiab qee cov lus nug yuav tau tham kom ntxaws hauv kab lus no.
Sartans
Cov pab pawg ntawm cov tshuaj nyob rau hauv kev txiav txim siab tseem hu ua raws li hauv qab no: angiotensin 2 receptor blockers. Cov tshuaj uas koom nrog pawg tshuaj no tau tsim los ntawm kev tshawb fawb txog qhov ua rau cov kab mob ntawm cov hlab plawv. Niaj hnub no, lawv siv nyob rau hauv cardiology yog ntau dua.
Angiotensin 2 receptor blockers: mechanism ntawm kev txiav txim
Ua ntej koj pib siv cov tshuaj, nws yog ib qho tseem ceeb kom nkag siab meej tias lawv ua haujlwm li cas. Yuav ua li cas angiotensin 2 receptor blockers cuam tshuam rau tib neeg lub cev? Cov tshuaj ntawm pab pawg no khi rau receptors, yog li thaiv kev nce ntshav siab. Qhov no yuav pab kom tsis txhob muaj ntshav siab. Angiotensin 2 receptor blockers yog cov tshuaj zoo tshaj plaws hauv qhov no. Cov kws tshwj xeeb tau mob siab rau lawv.
Angiotensin 2 receptor blockers: kev faib tawm
Muaj ntau hom sartans uas txawv hauv lawv cov qauv tshuaj. Nws muaj peev xwm xaiv cov blockers haum rau tus neeg mobangiotensin 2 receptors. Cov tshuaj tau teev tseg hauv qab no, nws yog ib qho tseem ceeb rau kev tshawb fawb thiab sib tham txog qhov tsim nyog ntawm kev siv nrog koj tus kws kho mob.
Yog li, muaj plaub pawg ntawm sartans:
- Biphenyl tetrazole derivatives.
- Non-biphenyl tetrazole derivatives.
- Non-biphenyl netetrazol.
- Non-cyclic compounds.
Yog li, muaj ntau ntau hom tshuaj rau hauv uas angiotensin 2 receptor blockers tau muab faib. Cov tshuaj (cov npe ntawm cov tseem ceeb) tau nthuav tawm hauv qab no:
- "Losartan".
- "Eprosartan".
- "Irbesartan".
- "Telmisartan".
- "Valsartan".
- "Candesartan".
Cov lus qhia rau kev siv
Koj tuaj yeem noj tshuaj ntawm pab pawg no tsuas yog raws li koj tus kws kho mob qhia. Muaj ntau qhov xwm txheej uas nws yuav tsim nyog siv angiotensin 2 receptor blockers.
- Hypertension. Nws yog tus kab mob no uas suav hais tias yog lub ntsiab lus qhia rau kev siv sartans. Qhov no yog vim lub fact tias angiotensin 2 receptor blockers tsis muaj kev cuam tshuam rau cov metabolism, tsis provoke erectile kawg, thiab tsis cuam tshuam bronchial patency. Cov nyhuv ntawm cov tshuaj pib ob mus rau plaub lub lis piam tom qab pib kho.
- Lub plawv tsis ua hauj lwm. Angiotensin II receptor blockers inhibit qhov kev ua ntawm renin-angiotensin-aldosterone system, uas nws ua haujlwm thiabprovokes kev loj hlob ntawm tus kab mob.
- Nephropathy. Vim muaj ntshav qab zib mellitus thiab arterial hypertension, mob hnyav hauv kev ua haujlwm ntawm lub raum tshwm sim. Angiotensin 2 receptor blockers tiv thaiv cov kab mob hauv nruab nrog cev thiab tiv thaiv cov protein ntau dhau los ntawm kev tawm hauv cov zis.
Losartan
Ib yam khoom siv tau zoo uas yog pawg ntawm sartans. "Losartan" yog angiotensin 2 receptor blocker-antagonist. Cov nyhuv ntawm cov tshuaj ua rau siab tshaj plaws tom qab 6 teev txij li lub sijhawm noj tshuaj. Cov txiaj ntsig xav tau yog ua tiav tom qab peb mus rau rau lub lis piam ntawm kev siv tshuaj.
Cov lus qhia tseem ceeb rau kev siv cov tshuaj no yog raws li hauv qab no:
- lub plawv tsis ua hauj lwm;
- hlab ntshav siab;
- txo qis kev pheej hmoo ntawm mob stroke hauv cov neeg mob uas muaj qhov yuav tsum tau ua ua ntej rau qhov no.
Nws yog txwv tsis pub siv "Losartan" thaum lub sijhawm yug menyuam thiab thaum pub niam mis, nrog rau cov xwm txheej ntawm tus kheej rhiab heev rau tus kheej cov tshuaj ntawm cov tshuaj.
Angiotensin 2 receptor blockers, uas cov tshuaj hauv nqe lus nug belongs, tuaj yeem ua rau qee yam kev mob tshwm sim, xws li kiv taub hau, insomnia, pw tsaug zog, tsis hnov tsw, tsis pom kev, tremor,Kev nyuaj siab, nco tsis meej, pharyngitis, hnoos, bronchitis, rhinitis, xeev siab, gastritis, toothache, raws plab, anorexia, ntuav, convulsions, mob caj dab, mob nyob rau hauv lub xub pwg nyom, nraub qaum, ceg, palpitations, anemia, impaired lub raum ua hauj lwm, impotence, tsis muaj zog libido. erythema, alopecia, tawm pob, pruritus, edema, kub taub hau, gout, hyperkalemia.
Noj tshuaj ib hnub ib zaug, tsis hais txog kev noj zaub mov, hauv koob tshuaj los ntawm koj tus kws kho mob.
Valsartan
Cov tshuaj no zoo txo qis myocardial hypertrophy, uas tshwm sim vim kev txhim kho ntawm arterial hypertension. Tsis muaj cov tsos mob tshem tawm tom qab txiav tawm cov tshuaj, txawm hais tias nws tshwm sim los ntawm qee qhov angiotensin 2 receptor blockers (cov lus piav qhia ntawm pab pawg sartans pab qhia meej tias cov tshuaj twg yog cov cuab yeej no).
Cov lus qhia tseem ceeb rau kev noj cov tshuaj hauv nqe lus nug yog cov xwm txheej hauv qab no: myocardial infarction, thawj lossis theem nrab kub siab, congestive plawv tsis ua haujlwm.
Tshuaj yog noj ntawm qhov ncauj. Lawv yuav tsum tau nqos tsis tau zom. Qhov koob tshuaj ntawm cov tshuaj yog muab los ntawm tus kws kho mob. Tab sis qhov siab tshaj plaws ntawm cov tshuaj uas tuaj yeem noj thaum nruab hnub yog rau pua plaub caug milligrams.
Qee zaum angiotensin receptor blockers tuaj yeem ua rau lub cev tsis zoo 2. Cov kev mob tshwm sim uas Valsartan tuaj yeem ua rau: txo libido, khaus, kiv taub hau, neutropenia, tsis nco qab,sinusitis, insomnia, myalgia, raws plab, anemia, hnoos, mob nraub qaum, vertigo, xeev siab, vasculitis, edema, rhinitis. Yog tias ib qho kev tshwm sim saum toj no tshwm sim, nrhiav kev kho mob tam sim.
Candesartan
Cov tshuaj hauv nqe lus nug yog tsim los ntawm cov ntsiav tshuaj rau kev siv qhov ncauj. Nws yuav tsum tau noj ib zaug lossis ob zaug ib hnub nyob rau tib lub sijhawm tsis hais noj mov. Koj yuav tsum ua tib zoo ua raws li cov lus pom zoo ntawm cov kws tshaj lij. Nws yog ib qho tseem ceeb tsis txhob tso tseg cov tshuaj txawm tias thaum koj hnov zoo dua. Txwv tsis pub, nws tuaj yeem ua rau tsis zoo ntawm cov tshuaj.
Thaum siv, ceev faj rau cov neeg mob ntshav qab zib, raum tsis ua haujlwm lossis nqa menyuam. Tag nrho cov xwm txheej no yuav tsum raug tshaj tawm rau cov kws tshaj lij.
Telmisartan
Cov tshuaj hauv nqe lus nug yog nqus los ntawm txoj hnyuv hauv lub sijhawm luv luv. Nws tuaj yeem noj nrog lossis tsis muaj zaub mov. Lub ntsiab lus qhia rau kev siv yog arterial hypertension. Ib nrab-lub neej ntawm cov tshuaj yog ntau tshaj nees nkaum teev. Cov tshuaj tau tawm los ntawm txoj hnyuv yuav luag tsis hloov.
Tsis txhob noj tshuaj thaum cev xeeb tub lossis pub niam mis.
Cov tshuaj yuav ua rau muaj kev phiv hauv qab noCov teebmeem: insomnia, kiv taub hau, xeev siab, raws plab, kev nyuaj siab, mob plab, pharyngitis, ua pob liab vog, hnoos, myalgia, urinary kab mob, tsis tshua muaj ntshav siab, mob hauv siab, palpitations, anemia.
Eprosartan
Cov tshuaj nug yuav tsum tau noj ib hnub ib zaug. Qhov pom zoo tus nqi ntawm cov tshuaj rau ib zaug siv yog rau puas milligrams. Cov nyhuv siab tshaj plaws yog ua tiav tom qab ob mus rau peb lub lis piam ntawm kev siv. "Eprosartan" tuaj yeem yog ob qho tib si ntawm txoj kev kho mob thiab cov ntsiab lus tseem ceeb ntawm kev kho mob monotherapy.
Tsis txhob siv cov tshuaj nug thaum cev xeeb tub lossis cev xeeb tub.
Cov kev phiv dab tsi tuaj yeem tshwm sim thaum siv "Eprosartan"? Ntawm lawv yog cov hauv qab no: qaug zog, raws plab, kiv taub hau, mob taub hau, rhinitis, hnoos, ua tsis taus pa, o, mob hauv siab.
Irbesartan
Cov tshuaj nug yog noj qhov ncauj. Nws yog absorbed los ntawm txoj hnyuv hauv lub sijhawm luv luv. Qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tshwm sim tom qab ib nrab mus rau ob teev. Kev noj haus tsis cuam tshuam rau kev ua tau zoo ntawm cov tshuaj.
Yog tias tus neeg mob tau txais kev kho hemodialysis, qhov no tsis cuam tshuam rau kev ua haujlwm ntawm Irbesartan. Cov tshuaj no tsis tau tawm ntawm tib neeg lub cev los ntawm hemodialysis. Ib yam li ntawd, cov tshuaj tuaj yeem ua rau muaj kev nyab xeeb los ntawm cov neeg mob uas mob ntshav siab me me mus rau nruab nrab.hnyav.
Tshuaj yuav tsum nqos tsis zom. Nws siv tsis tas yuav tsum tau ua ke nrog kev noj zaub mov. Qhov zoo tshaj plaws thawj koob tshuaj yog ib puas thiab tsib caug milligrams ib hnub twg. Cov neeg laus raug qhia kom pib kho nrog xya caum milligrams. Thaum kho, koj tus kws kho mob yuav txiav txim siab hloov qhov ntau npaum li cas (piv txwv li, txhawm rau nce nws, yog tias tsis muaj kev kho mob txaus rau lub cev). Nyob rau hauv cov ntaub ntawv no, tus neeg mob yuav tsum tau sau ib koob ntawm peb puas milligrams ntawm cov tshuaj los yog, nyob rau hauv lub hauv paus ntsiab lus, hloov cov tshuaj tseem ceeb. Piv txwv li, rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus thiab ntshav siab, cov koob tshuaj yuav tsum maj mam hloov ntawm ib puas thiab tsib caug milligrams ib hnub mus rau peb puas milligrams (qhov no yog cov tshuaj uas zoo tshaj plaws hauv kev sib ntaus sib tua nephropathy.).
Muaj qee yam ntawm kev siv tshuaj hauv nqe lus nug. Yog li, cov neeg mob raug kev txom nyem los ntawm kev ua txhaum ntawm dej thiab electrolyte tshuav, ua ntej pib kho, nws yog ib qho tsim nyog yuav tau tshem tawm qee qhov kev tshwm sim (hyponatremia).
Yog tias ib tus neeg muaj lub raum tsis ua haujlwm, ces nws txoj kev kho mob yuav zoo ib yam li tsis muaj teeb meem li ntawd. Tib yam siv rau qhov mob me mus rau nruab nrab lub siab ua haujlwm tsis zoo. Nyob rau tib lub sijhawm, nrog rau ib txhij hemodialysis, thawj tus nqi ntawm cov tshuaj yuav tsum tau muab faib ua ib nrab piv rau cov nyiaj li niaj zaus thiab yog xya caum tsib milligrams.ib hnub.
Cov kws tshaj lij tsis pom zoo siv cov tshuaj hauv nqe lus nug rau cov menyuam yaus, vim nws tseem tsis tau tsim kom muaj kev nyab xeeb thiab siv tau zoo npaum li cas rau cov neeg mob hnub nyoog no.
"Irbesartan" yog nruj me ntsis txwv tsis pub siv los ntawm cov poj niam uas muaj menyuam yaus, vim nws cuam tshuam ncaj qha rau kev loj hlob ntawm tus menyuam hauv plab. Yog tias cev xeeb tub tshwm sim thaum lub sijhawm kho, tom kawg yuav tsum tau muab tso tseg tam sim ntawd. Nws raug nquahu kom hloov mus rau kev siv tshuaj lwm yam txawm tias ua ntej pib npaj cev xeeb tub. Cov tshuaj hauv nqe lus nug tsis raug tso cai siv thaum pub niam mis, vim tsis muaj ntaub ntawv hais txog seb cov tshuaj no nkag mus rau hauv cov kua mis.
Kev saib xyuas kev noj qab haus huv yog lub luag haujlwm ntawm tus kheej ntawm txhua tus neeg. Thiab qhov loj dua koj tau, qhov kev siv zog ntau dua koj yuav tsum muab tso rau hauv. Txawm li cas los xij, kev lag luam kws tshuaj muab kev pabcuam tseem ceeb hauv qhov no, ua haujlwm tas li los tsim cov tshuaj zoo dua thiab siv tau zoo dua. Xws li nquag siv hauv kev sib ntaus tawm tsam cov kab mob plawv thiab cov angiotensin 2 receptor blockers tau tham hauv kab lus no. Cov tshuaj, cov npe uas tau muab thiab sib tham kom ntxaws hauv kab lus no, yuav tsum tau siv thiab siv raws li kws kho mob tau sau tseg, leej twg. yog paub zoo nrog tam sim no lub xeev ntawm kev noj qab haus huv ntawm tus neeg mob, thiab tsuas yog nyob rau hauv nws cov kev tswj tsis tu ncua. Ntawm cov tshuaj xws li "Losartan", "Eprosartan","Irbesartan", "Telmisartan", "Valsartan" thiab "Kandesartan". Cov tshuaj hauv nqe lus nug tsuas yog muab rau hauv cov xwm txheej hauv qab no: thaum muaj ntshav siab, nephropathy thiab lub plawv tsis ua haujlwm.
Yog tias koj xav pib kho tus kheej, nws yog ib qho tseem ceeb kom nco ntsoov qhov xwm txheej uas cuam tshuam nrog qhov no. Ua ntej, thaum siv cov tshuaj hauv nqe lus nug, nws yog ib qho tseem ceeb uas yuav tsum tau ua tib zoo saib xyuas cov tshuaj thiab qee zaum kho nws nyob ntawm tus neeg mob tam sim no. Tsuas yog tus kws tshaj lij tuaj yeem ua tiav tag nrho cov txheej txheem no raws li txoj cai. Txij li tsuas yog tus kws kho mob tuaj koom tuaj yeem, raws li kev tshuaj xyuas thiab cov txiaj ntsig ntawm cov kev sim, sau cov koob tshuaj uas tsim nyog thiab tsim kom muaj kev kho mob. Tom qab tag nrho, txoj kev kho yuav zoo tsuas yog tus neeg mob ua raws li tus kws kho mob cov lus pom zoo.
Ntawm qhov tod tes, nws yog ib qho tseem ceeb uas yuav tsum ua txhua yam ua tau los txhim kho koj tus kheej lub cev los ntawm kev ua raws li cov cai ntawm kev noj qab haus huv. Cov neeg mob zoo li no yuav tsum tau kho lawv cov kev pw tsaug zog thiab kev pw tsaug zog zoo, tswj cov dej sib npaug, thiab kho lawv cov kev noj qab haus huv (tom qab tag nrho, cov khoom noj tsis zoo uas tsis muab lub cev txaus rau cov as-ham tseem ceeb yuav tsis pub rov qab mus rau lub cev tsis zoo.).
Xaiv cov tshuaj zoo. Saib xyuas koj tus kheej thiab cov neeg koj hlub. Noj qab nyob zoo!
