Tam sim no, lub khw muag tshuaj nthuav tawm ntau yam tshuaj uas siv los kho cov kab mob hauv plab hnyuv. Yog li, ib qho ntawm cov tshuaj niaj hnub no yog cov tshuaj Nolpaza, uas tuaj yeem tshem tawm cov acidity ntawm lub plab. Lub tuam txhab kws tshuaj KRKA (Slovenia) koom nrog kev tsim cov tshuaj no.
Composition
Cov lus qhia rau kev siv "Nolpaza" muaj cov ntaub ntawv hais tias ib ntsiav tshuaj yuav muaj 20 lossis 40 mg ntawm pantoprazole (nyob rau hauv daim ntawv ntawm sodium ntsev) - lub ntsiab tivthaiv vim hais tias cov tshuaj muaj ib tug kho nyhuv.
Tsuas yog cov khoom siv ntxiv. Cov no suav nrog sorbitol, mannitol thiab ntsev (calcium stearate, sodium carbonate).
Mechanism of action
Cov tshuaj nquag ntawm cov tshuaj yog pantoprazole. Qhov no yog tiam tshiab ntawm proton twj tso kua mis inhibitors.
Lub tshuab ua haujlwm ntawm cov tshuaj yog tias nws tiv thaiv kev tsim cov enzyme lub luag haujlwm rau kev thauj mus loshydrogen ions nyob rau hauv lub lumen ntawm lub plab. Yog tias muaj ob peb ntawm lawv, ces hydrochloric acid tsuas yog tsis tsim. Yog li ntawd, ib puag ncig ntawm lub plab tsis ua acidic heev. Nov yog kev kho mob ntawm Nolpaza.
Nws tsim nyog sau cia tias cov tshuaj tsis tshem tawm cov kua qaub tag nrho, lub plab ib puag ncig tseem yuav nyob qis dua 7, tab sis nyob rau hauv qhov kev txwv.
Ib daim foos
Cov tshuaj muaj nyob rau hauv daim ntawv ntawm enteric-coated ntsiav tshuaj.
Cov ntawv sib txawv ntawm ntau npaum li cas thiab cov ntsiav tshuaj hauv ib pob. Nolpaza tuaj hauv 20mg thiab 40mg pantoprazole hauv txhua ntsiav tshuaj.
Pills, nyob rau hauv lem, tau ntim rau hauv hlwv thiab thawv ntawm 14, 28 los yog 56 daim.
Muaj lwm hom kev tso tawm ntawm cov tshuaj - lyophilisate rau kev npaj cov tshuaj txhaj tshuaj. Nws siv yog qhov tseem ceeb hauv kev kho mob hnyav, nrog rau cov txheej txheem pathological ntev hauv lub plab zom mov.
Pharmacodynamics
"Nolpaza" tau noj hauv qhov ncauj, tom qab ntawd pantoprazole tawm ntawm cov ntsiav tshuaj thiab nqus mus rau hauv lub cev.
Lub bioavailability ntawm cov tshuaj yog siab heev thiab yog kwv yees li 75-80%. Tib lub sijhawm, nws tsis nyob ntawm kev noj zaub mov.
Qhov siab tshaj plaws ntawm cov tshuaj tiv thaiv pom nyob hauv lub cev tom qab 2 teev.
Pantoprazole yuav luag tag nrho hauv daim siab, tom qab ntawd nws tawm hauv cov zis thiab qee qhov hauv cov quav (kwv yees li 5%).
Indications raudaim ntawv thov
Vim nws txoj kev ua haujlwm zoo, cov tshuaj siv rau:
- mob plab thiab hnyuv, hauv thaj tsam ntawm duodenum.
- Zollinger-Ellison Syndrome - kab mob uas muaj cov qog nqaij hlav hauv qee lub hlwb ntawm tus txiav.
- Ntxiv rau, "Nolpaza" tuaj yeem siv ua ke nrog cov tshuaj tua kab mob los rhuav tshem cov kab mob Helicobacter pylori.
- Cov lus qhia suav nrog reflux esophagitis - cov txheej txheem inflammatory ntawm cov hlab ntsha mucosa.
Contraindications rau kev siv
"Nolpaza" txwv tsis pub siv los ntawm cov neeg mob uas mob plab zom mov vim muaj teeb meem neurotic. Thaum siv cov tshuaj hauv qhov no, qhov xwm txheej tsuas yog tuaj yeem tshwm sim.
Tsis tas li ntawd, ua ntej koj pib noj cov tshuaj, koj yuav tsum tsis suav nrog cov kev kuaj mob xws li malignant neoplasms ntawm lub plab zom mov, txwv tsis pub Nolpaza yuav tshem tawm cov tsos mob ntawm oncology, yog li ncua nws qhov kev tshawb pom. Yog li ntawd, nyob rau hauv cov ntaub ntawv ntawm mob cancer ntawm lub digestive system, cov tshuaj no yog txwv tsis pub.
Lwm contraindication yog hypersensitivity rau ib feem ntawm cov tshuaj. Txwv tsis pub, xob laim-kev loj hlob sai ntawm kev ua xua muaj zog tuaj yeem ua tau.
Siv thaum cev xeeb tub thiab lactation
Raws li txoj cai, cov kws kho mob tau sau cov tshuaj no rau cov poj niam cev xeeb tub, tab sis tsuas yog thaum xav tau ceev, muab qhov txaus ntshai rau tus menyuam hauv plab.
Raws li cov ntaub ntawv los ntawm tag nrho cov lus qhia ntawm Nolpaza, nws yog txwv tsis pub noj tshuaj thaum pub niam mis. Qhov tseeb yog tias pantoprazole nkag mus rau hauv niam cov kua mis thiab tuaj yeem cuam tshuam tsis zoo rau tus menyuam lub cev.
tsis zoo tshwm sim
Thiab tuaj yeem hais li cas txog kev phiv ntawm "Nolpaza"? Zoo li lwm yam tshuaj, cov tshuaj muaj peev xwm sib txawv kom muaj kev cuam tshuam tsis zoo rau ntau lub cev thiab lub cev. Yog li ntawd, qee qhov kev mob tshwm sim tuaj yeem tshwm sim. "Nolpaza" tuaj yeem ua txhaum cai:
- Cov kab mob hauv plab: xeev siab, tsam plab, raws plab, mob epigastric.
- Cov kev mob tshwm sim ntawm "Nolpaza" tuaj yeem ua rau ntawm lub paj hlwb. Qhov no feem ntau tshwm sim raws li mob taub hau thiab kiv taub hau.
- daim tawv nqaij kuj raug kev txom nyem. Vim muaj pob khaus khaus khaus.
- Tsis tshua muaj, tab sis kev nyuaj siab, edema thiab kub taub hau tuaj yeem tshwm sim.
Thaum twg cov kev mob tshwm sim ntawm "Nolpaza" tshwm sim? Qhov no feem ntau tshwm sim hauv thawj lub lim tiam ntawm kev kho mob. Cov neeg mob pib yws ntawm pob khaus, mob taub hau, thiab lwm yam.
Raws li txoj cai, tag nrho cov kev mob tshwm sim ntawm "Nolpaza" sai sai ploj tom qab kho cov tshuaj lossis txiav tawm cov tshuaj.
koob tshuaj thiab txoj kev tswj hwm
Yog tias "Nolpaza" raug noj, ib ntsiav tshuaj, txawm tias xaivntau npaum li cas, yuav tsum tau nqos tag nrho, thiab ces ntxuav nrog ib tug txaus tus nqi ntawm cov dej huv. Feem ntau ib nrab ib khob kua yog txaus.
Koj tsis tas yuav zom, yaj cov tshuaj. Qhov no yuav cuam tshuam rau cov txheej txheem tso tshuaj. Tom qab tag nrho, nws yog ib qho tseem ceeb heev uas cov tshuaj tso tawm los ntawm lub lumen ntawm lub plab, thiab tsis nyob rau hauv lub qhov ncauj kab noj hniav.
Txawm hais tias tsis muaj kev sib raug zoo ntawm kev noj zaub mov thiab kev siv tshuaj, nws yog qhov zoo dua los noj tshuaj tam sim ua ntej noj mov.
Yog txoj kev kho mob uas kws kho mob tau sau tseg tias koj yuav tsum haus ib ntsiav tshuaj ib hnub, nws yog qhov zoo dua ua qhov no thaum sawv ntxov, ua ntej noj tshais.
Rau cov neeg mob uas mob reflux esophagitis, tus kws kho mob feem ntau sau 20 mg ntawm pantoprazole ib hnub ib zaug. Lub sijhawm ntawm chav kawm yog teem rau tus kheej rau txhua tus neeg mob, tab sis feem ntau tsis pub dhau ib hlis. Txawm hais tias qee zaus tus neeg raug yuam kom noj tshuaj tau ob lub hlis.
Yog tias muaj qhov yuav rov qab los, qhov koob tshuaj tau nce ib ntus mus rau 40 mg rau 1-2 lub lis piam, tom qab ntawd qhov koob tshuaj rov qab mus rau 20 mg ib hnub.
Muaj ib pawg ntawm cov neeg uas raug yuam kom siv cov tshuaj uas tsis yog-steroidal anti-inflammatory (ibuprofen, dexalgin thiab lwm yam) ntev, uas muaj kev cuam tshuam tsis zoo rau cov phab ntsa ntawm cov hlab ntsha. Txhawm rau tiv thaiv lub plab zom mov, cov neeg zoo li no tau muab 20 mg ntawm pantoprazole ib hnub.
Txhawm rau rhuav tshem Helicobacter pylori "Nolpaza" yuav tsum tau siv nrog kev kho tshuaj tua kab mob, 40 txhuamg 2 zaug ib hnub.
Cov koob tshuaj ntau tshaj yog qhia rau cov neeg mob uas mob Zollinger-Ellison syndrome thiab cov kab mob zoo sib xws uas muaj qhov tshwj xeeb muaj zog ntawm hydrochloric acid. Cov kev kho mob rau cov xwm txheej zoo li no yog ob zaug ntau npaum li 40 mg. Yog tias tsim nyog, tus neeg mob yuav raug muab tshuaj 80 mg 2 zaug hauv ib hnub.
Nws yuav tsum tau coj mus rau hauv tus account tias yog tias tus neeg mob muaj qhov txawv txav hauv daim siab, ces nws pom tsis ntau tshaj 20 mg ntawm pantoprazole ib hnub.
Ua ntej pib kho, yuav tsum tsis suav nrog cov qog nqaij hlav hauv tus neeg mob lub plab thiab txoj hlab pas.
Cov lus qhia rau kev siv tshuaj Nolpaza hais tias cov tshuaj yuav tsum tau npaj tam sim ua ntej kev tswj hwm.
Pantoprazole hmoov yuav tsum tau yaj hauv 10 ml ntawm sodium chloride 0.9% (saline) thiab muab tso rau hauv cov hlab ntsha. Tsis tas li ntawd, kev taw qhia ntawm cov tshuaj drip yog txais. Ua li no, cov tshuaj yuav tsum tau tov nrog 100 ml ntawm saline los yog 5% qabzib tov.
Nws yog ib qho tseem ceeb heev uas yuav tau pib txhaj tshuaj 2-15 feeb tom qab kev npaj cov tshuaj. Tsis tas li ntawd, daim foos no yuav tsum tau siv tsuas yog thaum qhov ua tau zoo ntawm daim ntawv ntawm qhov ncauj tsis txaus.
Cov ntsiab lus ntawm kev xa tawm los ntawm chaw muag tshuaj
"Nolpaza", uas muaj 40 mg ntawm pantoprazole, yog hais txog cov tshuaj uas tau muab tso rau hauv daim ntawv tshuaj xwb. Yog li ntawd, cov tshuaj tsis muaj kev ywj pheej rau tus neeg yuav khoomnrhiav. Ua ntej muag tshuaj, tus kws muag tshuaj lossis tus kws muag tshuaj yuav nug tus neeg mob txog daim ntawv xaj ntawm daim ntawv teev tseg nruj me ntsis, xyuas kom raug thiab tom qab ntawd tso cov tshuaj.
Nolpaza 20mg tuaj yeem muag yam tsis muaj tshuaj.
Cov Cai thiab cov cai ntawm kev cia
"Nolpaza" yuav tsum muab cia rau hauv qhov chaw qhuav, deb ntawm tshav ntuj ncaj qha. Cov huab cua kub yuav tsum tsis txhob qis dua 15 thiab tsis siab tshaj 30 degrees.
Nws yog ib qho tseem ceeb heev uas yuav tsum khaws cov ntsiav tshuaj no kom deb ntawm cov me nyuam yaus.
Raws li cov xwm txheej tsim nyog, cov khoom tuaj yeem khaws cia rau ob xyoos txij li hnub tsim khoom.
Reviews
Vim li cas Nolpaza tau sau ntau zaus? Raws li txoj cai, rau kev kho mob peptic ulcer ntawm lub plab thiab cov hnyuv.
Yog koj kawm paub meej cov kev tshuaj xyuas ntawm cov neeg mob txog cov tshuaj no, peb tuaj yeem xaus tias kwv yees li 70% ntawm lawv yog qhov zoo.
Cov neeg feem coob uas tau kho nrog cov tshuaj no thov tias cov tshuaj no tshem tawm cov tsos mob tsis zoo. Xav tias zoo dua tom qab ib hnub lossis ob hnub tom qab pib noj tshuaj.
Qhov tsis zoo tseem ceeb uas tuaj yeem pom hauv kev tshuaj xyuas ntawm "Nolpaz" yog cov kev mob tshwm sim, uas qee zaum tshwm sim heev. Ib feem me me ntawm cov neeg mob yuav tsum tsis txhob noj tshuaj lossis txo nws cov koob tshuaj.
Qhov thib ob qhov tsis zoo yog tus nqi kho mob siab. Tom qab tag nrho, muaj cov tshuaj pheej yig dua ntawm cov khw muag tshuaj nrogzoo ib yam tab sis tsis ua tib yam.
Txawm li cas los xij, tsis muaj qhov tsis ntseeg tias cov tshuaj yuav ua rau nws raug nqi. Tom qab tag nrho, pantoprazole yog ib qho ntawm cov tshuaj zoo tshaj plaws uas txo cov acidity ntawm lub plab. Tib lub sijhawm, qhov kev kho no ua rau tsis muaj kev phiv heev.
Cov txiaj ntsig kho mob tshwj xeeb yog pom tau thaum siv cov tshuaj txhaj tshuaj. Raws li kev txheeb xyuas, cov txiaj ntsig pom tau pom tom qab ib lossis ob qhov kev txhaj tshuaj. Txawm li cas los xij, tsis txhob hnov qab tias txoj kev siv "Nolpaza" yog tso cai tsuas yog nyob rau hauv cov xwm txheej hnyav thiab tsuas yog thaum kws kho mob tau sau tseg. Tsis tas li ntawd, cov kev phiv ntawm "Nolpaza" nyob rau hauv daim ntawv ntawm kev txhaj tshuaj, raws li txoj cai, manifest lawv tus kheej pronounced ntau.
Cov kws kho mob thiab kws kho mob plab hais lus zoo txog cov tshuaj, muab tshuaj rau lawv cov neeg mob rau ntau yam kab mob thiab cov tsos mob. Lawv xaiv cov tshuaj vim:
- Kev ntseeg siab ntawm nws qhov zoo.
- Nws haum rau cov neeg mob feem ntau.
- Cov neeg mob tsis pib yws tias tus kws kho mob tau sau cov tshuaj kim tshaj plaws. Qhov no cuam tshuam rau lub koob npe nrov ntawm tus kws tshaj lij.
- Cov tshuaj tsis tshua muaj tshwm sim hnyav.
Qhov xav tau ntau npaum li cas ntawm "Nolpaza" thiab hom kev tswj hwm raug muab cov txiaj ntsig kho tau zoo tshaj plaws nrog qhov tsawg kawg ntawm qhov tsis zoo.
Tus nqi tshuaj
Tus nqi nyob ntawm qhov xaiv ntau npaum li cas thiab daim ntawv tso tawm. Yog li, ntau pantoprazole muaj nyob rau hauv ib ntsiav tshuaj thiab ntau ntawm cov ntsiav tshuaj no nyob rau hauv pob, tus nqi siab dua.
"Nolpaza" 20mg:
- 14 ntsiav tshuaj - 130-180 rubles.
- 28 ntsiav tshuaj - 240-290 rubles.
- 56 ntsiav tshuaj - 350-400 rubles.
"Nolpaza" 40 mg:
- 14 ntsiav tshuaj - 200-250 rubles.
- 28 ntsiav tshuaj - 380-430 rubles.
- 56 ntsiav tshuaj - 580-630 rubles.
Analogues
"Nolpaza" yog hais txog cov tshuaj uas muaj kev xaiv nplua nuj ntawm cov qauv analogues.
Cov tshuaj muaj pantoprazole raws li cov khoom xyaw nquag muaj xws li tshuaj xws li:
- "Controllock" (Lub Tebchaws Yelemees).
- "Sanpraz" (India).
- Ultera (Russia).
Tag nrho cov tshuaj no muaj tib cov lus qhia thiab contraindications, kev phiv thiab kev siv tshuaj. Ntxiv rau, lawv yog txhua yam tshuaj noj.
Lawv sib txawv ntawm ib leeg los ntawm cov chaw tsim khoom thiab nqe cai. Raws li txoj cai, cov tshuaj Lavxias thiab Indian yog pheej yig dua li lawv cov khoom siv German.
Yog li, piv txwv li, "Controllock" yuav raug nqi tus neeg yuav khoom 300-350 rubles rau 14 ntsiav tshuaj uas muaj 20 mg ntawm pantoprazole txhua. Thiab ntawm 590-640 rubles - rau 28 ntsiav tshuaj ntawm 40 mg.
"Sanpraz" yuav raug nqi kwv yees li 470-520 rubles rau 1 pob uas muaj 30 ntsiav tshuaj ntawm 40 mg.
Yog li, peb tuaj yeem xaus tias "Nolpaza" yog nyob rau hauv cov nqi nruab nrab.
Zoo kawg
Cov tshuaj uas tsab xov xwm no tau mob siab rau yog ib qho txiaj ntsig zoo los txo qisplab acidity. Txawm li cas los xij, ua ntej pib qhov kev txais tos, koj yuav tsum tau txais ib tus kws kho mob cov tshuaj, ua kom paub koj tus kheej nrog cov contraindications thiab kev phiv ntawm Nolpaza.
Qhov tseeb yog tias cov tshuaj muaj kev cuam tshuam rau tib neeg lub cev, yog li qee zaus nws tuaj yeem ua rau qee yam teeb meem. Lwm qhov tsis zoo ntawm cov khoom yog nws tus nqi.
Analogues ntawm "Nolpaza" yog qhov dav dav sawv cev ntawm cov chaw muag tshuaj, uas tso cai rau tus neeg mob xaiv qhov kev xaiv zoo tshaj plaws ntawm txhua tus neeg sawv cev ntawm pantoprazole. Txawm li cas los xij, raws li cov txiaj ntsig ntawm kev tshawb fawb ntawm cov tshuaj analogues, nws tuaj yeem txiav txim siab tias Nolpaza sawv cev rau qhov zoo ntawm qhov zoo thiab tus nqi ntawm cov tshuaj uas muaj pantoprazole.
