Monocytes, cov qe ntshav tshwj xeeb, qee zaum hu ua cov ntaub so ntswg macrophages lossis phagocytic mononuclear hlwb. Lawv lub hom phiaj, tsis hais lub npe, yog los ntxuav lub cev ntawm cov hlwb tuag, neutralize antigens thiab cov kab mob, thiab tawm tsam cytotoxic xwm ntawm cov qog hlwb. Monocytes yog tsim nyob rau hauv cov pob txha pob txha, tam sim ntawd tom qab lawv tshwm sim, lawv nkag mus rau hauv peripheral cov hlab ntsha, qhov chaw uas lawv ncig pib rau 3-4 hnub. Tom qab ntawd lawv nkag mus rau hauv cov ntaub so ntswg thiab tau txais cov khoom ntawm cov ntaub so ntswg macrophages muaj. Nce monocytes qhia txog cov txheej txheem inflammatory hauv lub cev.
Monocyte-macrophages
Lub hom phiaj tseem ceeb ntawm monocyte-macrophages yog phagocytosis nrog kev nqus ntawm cov khoom txawv teb chaws nyob hauv lub cev. Cells tau txais lub zog los ntawm aerobic thiab anaerobic glycolysis, uas ua rau lawv ua haujlwm hauv thaj chaw ntawm cov kab mob pathological ntawm lub cev. Txij li thaum lawv yog ib hom ntawm cov qe ntshav dawb, lawv tau koom nrog cov txheej txheem tiv thaiv.kab mob ua ke nrog lwm cov hlwb ntawm pawg leukocyte: basophils, lymphocytes thiab neutrophils. Nyob rau hauv cov ntaub ntawv ntawm mob hnyav hauv zos hauv lub cev, theem ntawm monocytes nce.
monocytosis
Monocytes nce mus txog 8-9% tsis ua rau muaj kev txhawj xeeb. Yog tias lawv cov feem pua tau dhau los ntau dua 10%, qhov no qhia tau tias qhov pib ntawm monocytosis. Qhov xwm txheej ntawm monocytosis tsis meej, nws tuaj yeem tshwm sim hauv ib daim ntawv txheeb ze, nrog me ntsis dhau ntawm cov qauv hauv lub cev, tab sis nws tuaj yeem dhau los ua qhov tseeb thaum qib siab tshaj 10%. Raws li txoj cai, monocytosis kiag li yog nrog los ntawm kev txo qis ntawm lwm cov leukocytes. Cov qauv no tau pom nyob rau hauv cov ntaub ntawv ntawm lymphocytopenia thiab neutropenia thiab yog ib yam rau cov neeg laus.
Monocytes ceeb toom
siab monocytes yog qhov laj thawj los nrhiav kev tsom mus rau qhov mob lossis qee yam kab mob, feem ntau kis tau. Koj yuav tsum ua kom tiav cov ntshav. Qee zaum, cov poj niam raug kuaj cev xeeb tub. Kev nce qib ntawm monocytes hauv cov ntshav tshwm sim nrog cov kab mob hauv qab no: kab mob los yog kab mob fungal, rickettsial thiab protozoal, kab mob endocarditis. Los ntawm cov kab mob ntawm cov hlab plawv, myeloid leukemia, monocytic myeloid leukemia yog ua tau. Los ntawm cov kab mob granulomatous - enteritis thiab ulcerative colitis, tuberculosis, brucellosis, syphilis.
Childhood monocytosis
Monocytes nce hauv cov menyuam yaus lub cev ua tau zoo ib yamLub luag haujlwm, zoo li hauv ib tus neeg laus, txawm li cas los xij, cov menyuam yaus lub monocytosis txawv me ntsis hauv nws qhov kev ua tau zoo. Kev nce qib ntawm macrophage monocytes nyob rau hauv tus me nyuam tshwm sim nrog ib qho kev mob, tab sis nws kuj kis tau sai yog tias qhov kev kuaj mob raug tsim nyog thiab kev kho mob tsim nyog tau ua tiav. Lawv cov ntsiab lus nyob rau hauv cov ntshav ntawm tus me nyuam nyob ntawm lub hnub nyoog: nyob rau hauv ib tug me nyuam mos los ntawm 3 mus rau 12%, mus txog rau ob lub lis piam 5-15%, los ntawm 2 lub lis piam mus rau 1 xyoo 4-10%, los ntawm 1 xyoo mus rau 2 xyoo 3- 10%, los ntawm 2 mus rau 5 xyoo 3-9%, los ntawm 6 mus rau 16 xyoo 3-9%, tom qab 16 xyoo 3-9%. Ntau cov monocytes hauv cov ntshav ntawm tus menyuam tuaj yeem ua rau muaj kab mob sib kis, mob caj dab thaum yau, mob caj dab nodular.
