Nws tsis muaj qhov zais cia tias cov tshuaj tua kab mob semi-synthetic muaj ntau qhov kev ua haujlwm. Cov tshuaj no yog siv los kho ntau yam kab mob inflammatory thiab kis kab mob. Tab sis ua ntej yuav sau cov tshuaj no, tus kws kho mob yuav tsum pom zoo kom tus neeg mob mus kuaj mob. Nov yog tib txoj hauv kev kom nkag siab tias cov tshuaj tua kab mob twg yuav ua tau zoo hauv kev kho ib tus kab mob.
Rau kev kho mob ntawm cov kab mob genitourinary, nrog rau cov kab mob ua pa, kev txhaj tshuaj "Cefotaxime" tau siv. Peb yuav xav txog cov yam ntxwv ntawm cov tshuaj no, nws cov contraindications, ntau npaum li cas thiab txoj kev ntawm kev tswj me ntsis ntxiv.
Kev sib xyaw, piav qhia, daim ntawv thiab ntim cov tshuaj
Cefotaxime muaj cov khoom xyaw dab tsi? Kev txhaj tshuaj (rau cov menyuam yaus, qhov ntau npaum li cas ntawm cov tshuaj no yog teem rau tus kheej) suav nrog cov tshuaj nquag xws li cefotaxime (sodium ntsev).
Cov tshuaj nws tus kheej yog cov hmoov dawb lossis daj, uas yog siv los npaj cov tshuaj npaj rau kev txhaj tshuaj rau hauv cov hlab ntsha lossis kev txhaj tshuaj intramuscular.
Tshuajmuaj nyob rau hauv iav fwj ntim rau hauv cartons.
tshuaj muaj txiaj ntsig
Koj puas paub tias Cefotaxime yog dab tsi? Cov lus qhia rau kev siv (kev txhaj tshuaj rau cov menyuam yaus tsis yog ib qho kev sim yooj yim, tab sis yuav ua li cas yog tias qhov kev xav tau zoo li no yog siav?) hais tias cov tshuaj tau muab rau cov neeg mob me me nrog kev ceev faj heev, vim tias nws yog cov tshuaj tua kab mob semi-synthetic. Nws cov khoom xyaw nquag raug cais raws li tiam thib peb cephalosporin.
Cov tshuaj no yog siv los ntawm niam txiv. Nws yog nquag tawm tsam gram-zoo flora, nrog rau cov kab mob gram-tsis zoo, uas muaj zog heev rau cov teebmeem ntawm aminoglycosides, sulfonamides thiab penicillin.
Lub hauv paus ntsiab lus ntawm cov tshuaj tiv thaiv kab mob ntawm cov tshuaj no yog ua raws li nws lub peev xwm los cuam tshuam kev ua haujlwm ntawm transpeptidase. Qhov no tshwm sim vim qhov thaiv ntawm peptidoglycan.
Kinetic nta ntawm cov tshuaj
Cefotaxime absorbed li cas? Cov lus piav qhia (kev txhaj tshuaj yog tib daim ntawv ntawm cov tshuaj hais) qhia tias tom qab txhaj tshuaj intramuscular, qhov siab tshaj plaws ntawm cov tshuaj hauv cov ntshav tau pom tom qab 35 feeb. Kwv yees li 27-40% ntawm cov tshuaj nquag khi rau cov ntshav plasma proteins.
Cov kab mob bactericidal ntawm cov tshuaj kav ntev li 12 teev. Cov tshuaj muaj nyob rau hauv lub gallbladder, myocardium, pob txha thiab cov ntaub so ntswg.
Nws tsis tuaj yeem hais tias cov tshuaj nquag ntawm cov tshuaj no tuaj yeem nkag muslos ntawm cov placenta thiab kuj nyob rau hauv pleural, peritoneal, synovial, cerebrospinal thiab pericardial kua.
Txog 90% ntawm cov tshuaj tau tawm hauv cov zis.
Nrog kev txhaj tshuaj intramuscular, ib nrab-lub neej ntawm cov tshuaj yog 60-90 feeb, thiab nrog kev txhaj tshuaj - 1 teev. Ib feem active ingredient yog excreted nyob rau hauv cov kua tsib. Tsis muaj tshuaj loog.
Cov lus qhia rau kev siv
Yuav siv cov tshuaj tua kab mob "Cefotaxime" li cas? Cov lus qhia rau kev siv (txhaj tshuaj, tus nqi uas tau teev tseg hauv qab no, yuav tsum tsuas yog kws kho mob tau sau tseg) hais tias cov tshuaj no tau qhia tias muaj kab mob sib kis.
Nws feem ntau siv rau hauv cov kab mob hauv qab no ntawm cov kab mob ua pa:
- pneumonia;
- pleurisy;
- abscesses;
- bronchitis.
Tsis tas li, kev kho mob raws li kev txiav txim siab siv tau thaum:
- kab mob meningitis;
- endocarditis;
- kev nyuaj siab tom qab;
- septicemia;
- cov ntaub so ntswg thiab pob txha kab mob;
- kab mob Lyme;
- kab mob urinary, caj pas, pob ntseg, qhov ntswg, raum;
- kab mob pob txha thiab pob txha;
- kab mob plab;
- kab mob tshwm sim los ntawm kev tiv thaiv kab mob.
Nws tseem yuav tsum tau sau tseg tias kev txhaj tshuaj Cefotaxime feem ntau tau sau los tiv thaiv kev kis kab mob uas tau tsim tom qab kev phais mob (xws liurological, obstetric-gynecological, ntawm lub plab hnyuv, thiab lwm yam).
Contraindications rau kev siv tshuaj
Hais txog yuav ua li cas dilute qhov kev txhaj tshuaj ntawm "Cefotaxime", peb yuav qhia me ntsis qis dua. Nws yuav tsum raug sau tseg tias qhov kev kho no tsis muaj cov npe ntev heev ntawm contraindications. Raws li cov lus qhia, cov tshuaj no tsis raug sau rau:
- ntshav;
- xeeb tub;
- tus neeg mob siab rau cov khoom xyaw nquag;
- enterocolitis (nrog rau keeb kwm).
Kuv puas tuaj yeem muab tshuaj Cefotaxime rau tus menyuam? Kev txhaj tshuaj rau cov menyuam yaus (kev tshuaj xyuas txog kev ua tau zoo ntawm cov tshuaj tau hais hauv qhov kawg ntawm tsab xov xwm) raug tso cai ua tom qab tus neeg mob muaj hnub nyoog 2.5 xyoo (rau kev txhaj tshuaj intramuscular).
Nrog kev saib xyuas tshwj xeeb, cov tshuaj tau muab rau cov menyuam mos yug tshiab, thaum pub mis niam (vim cov tshuaj tau tso tawm me me nrog niam cov kua mis), nrog rau thaum muaj lub raum tsis ua haujlwm thiab UC (suav nrog keeb kwm).
Thaum muaj kab mob ntawm lub raum thiab lub raum, tus neeg mob yuav tsum tau mus kuaj mob ntxiv kom tau txais kev txiav txim siab tias tsis muaj contraindications rau kev kho tshuaj tua kab mob.
Tshuaj "Cefotaxime": cov lus qhia rau kev siv (txhaj tshuaj)
Yuav ua li cas dilute cov hmoov kom raug? Txhawm rau teb cov lus nug no, saib cov lus qhia txuas nrog. Nws piav qhia ntxaws txog txoj hauv kev npaj cov tshuaj txhaj tshuaj.
Yog, rau cov leegkev tswj hwm (txhaj tshuaj) ntawm cov tshuaj 1 g ntawm hmoov yog diluted nrog 4 ml dej rau kev txhaj tshuaj (sterile). Cov tshuaj tiav yog txhaj maj mam li 4-7 feeb.
Rau cov tshuaj txhaj, 1-2 g ntawm hmoov yog diluted nrog 50 lossis 100 ml ntawm cov kuab tshuaj. Raws li nws yog siv 0.9% sodium chloride tov los yog 5% qabzib (dextrose) tov. Lub sij hawm ntawm qhov kev taw qhia yog 55-65 feeb.
YRau kev tswj hwm intramuscular ntawm ib qho tshuaj, 1 g ntawm hmoov yog yaj hauv 4 ml ntawm cov kuab tshuaj. Raws li nws siv dej rau kev txhaj tshuaj lossis 1% kev daws ntawm lidocaine.
Yog li, cov tshuaj hauv nqe lus nug tuaj yeem muab tso rau hauv cov hlab ntsha los ntawm kev tso dej los yog dav hlau, nrog rau intramuscularly.
Cov tshuaj feem ntau yog muab rau cov neeg laus, nrog rau cov tub ntxhais hluas hnub nyoog tshaj 12 xyoos uas hnyav tshaj 50 kg. Thaum xav tau sai, nws yog siv los kho cov menyuam yaus.
Tshuaj ntau ntau
Tam sim no koj paub yuav ua li cas koj tuaj yeem dilute Cefotaxime txhaj tshuaj. Tab sis lawv cov koob tshuaj yog dab tsi? Nws nyob ntawm qhov qhia thiab qhov hnyav ntawm tus kab mob.
Rau cov kab mob urinary, nrog rau cov kab mob tsis sib xws, cov tshuaj tau muab tso rau hauv cov hlab ntsha lossis intramuscularly, 1 g txhua 9-12 teev.
Rau tus kab mob nruab nrab, 1-2 g txhua 12 teev.
Rau tus mob gonorrhea tsis yooj yim, cov tshuaj tau muab tshuaj intramuscularly ntawm ib koob ntawm 1 g (ib zaug).
Hauv cov kab mob hnyav (xws li mob meningitis), cov tshuaj siv rau hauv cov hlab ntsha ntawm 2 g txhua 6-9 teev. Qhov siab tshaj plaws koob tshuaj ib hnub twg yog 12 g. Lub sijhawm ntawm kev kho mob yog teem rau tus kheej.
Txhawm rau tiv thaiv kev txhim kho ntawm cov kab mob sib kis ua ntej kev phais, tus neeg mob thaum lub sij hawm induction ntawm tshuaj loog yog muab ib koob tshuaj Cefotaxime ntawm ib koob ntawm 1 g. Yog tias xav tau, txhaj tshuaj yog rov ua dua tom qab 6-12 teev.
Thaum qhov kev phais mob, nyob rau hauv tus txheej txheem ntawm clamping lub umbilical leeg, cov tshuaj yog muab intravenously nyob rau hauv tus nqi ntawm 1 g. Tom qab ntawd, tom qab 6-12 teev, ib qho kev txhaj tshuaj ntxiv yog muab rau hauv tib koob tshuaj.
Kev qhia rau menyuam yaus
Yog tias tsim nyog, txhaj tshuaj "Cefotaxime" rau cov menyuam yug tshiab, nrog rau cov menyuam mos ntxov ntxov uas muaj hnub nyoog qis dua 1 lub lis piam, tau muab tso rau hauv qhov nyiaj ntawm 50 mg ib kg ntawm lub cev qhov hnyav txhua 12 teev. Thaum muaj hnub nyoog 1-4 lub lis piam, cov tshuaj tau muab rau tib koob, tab sis txhua txhua 9 teev.
Cov menyuam yaus hnub nyoog qis dua 2.5 xyoos uas hnyav dua 50 kg tau muab tshuaj intramuscularly lossis intravenously ntawm 50-180 mg ib kg ntawm lub cev hnyav (hauv 4 lossis 6 txhaj tshuaj).
Hauv cov kab mob sib kis hnyav, suav nrog mob meningitis, cov tshuaj noj txhua hnub tau nce mus rau 100-200 mg ib kg. Hauv qhov no, kev txhaj tshuaj yog nqa tawm intramuscularly lossis intravenously ntawm 4-6 zaug ib hnub. Qhov siab tshaj plaws ntawm cov tshuaj ib hnub yog 12 g.
Side effects
Tawm tsam keeb kwm ntawm kev siv tshuaj "Cefotaxime", cov neeg mob tuaj yeem tsim cov tshuaj tiv thaiv hauv zos xws li:
- mob thaum siv tshuaj intramuscularly;
- phlebitis tsim kho nrog cov tshuaj intravenous.
Kuj tauCov teebmeem uas tsis xav tau hauv qab no raug sau tseg:
- cholestatic jaundice, pseudomembranous colitis;
- kab mob siab, xeev siab, hypoprothrombinemia;
- nce ALT, AST, hemolytic anemia;
- mob raws plab, txo platelet suav;
- ntuav, neutropenia.
Nyob tsis tshua muaj, cov lus teb tsis haum (eosinophil nce, angioedema thiab pruritus), nrog rau cov kab mob nephritis thiab candidiasis, ua tau.
Yog tias pom muaj lwm yam teebmeem tsis zoo, yuav tsum muaj kev pabcuam khomob thiab rho tawm tus kheej ntawm cov tshuaj.
Price thiab analogues ntawm cov tshuaj tua kab mob
Tus nqi ntawm cov tshuaj hauv nqe lus nug yog nyob ntawm cov npoo ntawm lub network thiab thaj tsam ntawm kev muag khoom. Qhov nruab nrab, ampoules-vials (5 daim ntawm 1 g txhua) tuaj yeem yuav rau 160-170 rubles.
Yog tias tsim nyog, cov tshuaj no tuaj yeem hloov nrog cov tshuaj zoo sib xws xws li Klaforan, Cefabol thiab Cefosin.
Txawm li cas los xij, nws yuav tsum tau sau tseg tam sim ntawd tias cov tshuaj no tuaj yeem siv tau tom qab sab laj nrog kws kho mob xwb.
Tshuaj tua kab mob
Hauv kev xyaum menyuam yaus, cov tshuaj no feem ntau tau muab tshuaj ua tshuaj tua kab mob. Raws li txoj cai, qhov no yog ua nyob rau hauv rooj plaub uas lwm cov tshuaj tua kab mob tsis muab kev kho mob zoo.
Cov neeg siv tshuaj xyuas ntawm kev txhaj tshuaj Cefotaxime yog qhov zoo dua. Cov ntawv ceeb toom ntawm tus neeg mob paub meej tias nws cov tshuaj tiv thaiv kab mob siab. Txawm li cas los xij, koj tuaj yeem nrhiav tau cov lus teb uas ncaj qha qhia qhov muaj nyob ntawmMuaj ntau qhov tsis zoo tshwm sim tom qab kev kho mob (bloating, dysbacteriosis, colic thiab lwm yam).
