Peb coob leej tau ntsib teeb meem pw tsaug zog tsawg kawg ib zaug hauv peb lub neej. Yog tias qhov no tau dhau los ua ib qho tshwm sim rau koj thiab cuam tshuam rau koj lub neej txhua hnub, koj tuaj yeem hais tau yam tsis muaj kev cuam tshuam hauv cov txheej txheem physiological hauv lub xeev uas muaj qhov tsawg kawg nkaus ntawm lub hlwb ua haujlwm thiab cov lus teb tsis muaj zog rau lub ntiaj teb ib puag ncig. koj. Vim kev pw tsaug zog tsis zoo, tsis tsuas yog qaug zog tshwm, tab sis kuj muaj kev puas siab puas ntsws thiab kev noj qab haus huv tsis zoo. Yog tias koj muaj teeb meem ntawm qhov xwm txheej no, cov tshuaj "Somnol" yuav los pab koj. Cov lus qhia rau kev siv, kev piav qhia ntawm cov tshuaj siv tshuaj, tshuaj xyuas cov kws kho mob thiab cov neeg mob, nrog rau cov tshuaj sib npaug sib npaug ntawm cov tshuaj tau tham hauv cov khoom no.
Daim foos thiab muaj pes tsawg leeg
Cov tshuaj hauv lub network ntawm cov khw muag tshuaj tuaj hauv daim ntawv ntawm biconvex cov ntsiav tshuaj dawb hauv lub plhaub, nyob rau sab xub ntiag uas muaj cov cim. Lawv tau ntim rau hauv hlwv ntawm 10 daim. Ib ntsiav tshuaj Somnol muaj 7.5 mg ntawm zopiclone,qos yaj ywm starch, magnesium stearate, calcium hydrogen phosphate anhydrous, sodium glycolate, silicon dioxide, aerosil, thiab povidone thiab xim.
Pharmacodynamics
Cov khoom tseem ceeb uas yog ib feem ntawm "Somnol" yog ib qho tshuaj tsaug zog uas yog pawg ntawm cyclopyrrolone. Zopiclone muaj hypnotic, sedative, anticonvulsant, tranquilizing thiab nqaij relaxant nyhuv. Cov tshuaj pharmacological no yog vim qhov kev ua ntawm cov khoom tseem ceeb ntawm cov receptors ntawm lub paj hlwb.
Thaum noj cov tshuaj, cov khoom tseem ceeb ntawm uas yog zopiclone, lub sijhawm pw tsaug zog thiab qhov zaus ntawm kev pw tsaug zog thaum hmo ntuj txo qis, lub sijhawm pw tsaug zog thiab nws qhov zoo nce.
Nrog kev kho mob ntev, txog li 4 lub hlis, cov tshuaj Somnol tsis yog tshuaj (cov lus qhia rau kev siv qhia qhov no).
Pharmacological action
Qhov sib txawv tseem ceeb ntawm Somnol thiab lwm yam tshuaj tsaug zog yog qhov muaj nyob rau hauv nws cov tshuaj muaj pes tsawg leeg hu ua zopiclone. Cov cuab yeej no txo qis lub sijhawm pw tsaug zog, txhawb kev pw tsaug zog tom qab nws pib, tsis ua txhaum qhov kev hloov ntawm cov theem thiab nws qhov zoo. Cov nyhuv ntawm cov tshuaj tshwm sim ib nrab ib teev tom qab noj nws thiab kav rau 6-8 teev, uas coincides nyob rau hauv lub sij hawm nrog rau lub sij hawm ntev ntawm lub cev, ntuj physiological txheej txheem ntawm nyob rau hauv lub xeev nrog tsawg kawg nkaus lub paj hlwb kev ua si thiab ib tug txo cov tshuaj tiv thaiv rau dab tsi yog. tshwm sim ib ncig.
Tsis zoo li barbiturates thiab benzodiazepines, qhov kev xav ntawm kev qaug zog thiab qaug zog tsis tshwm sim thaum noj tshuaj"Somnol". Cov lus qhia rau kev siv qhia tau hais tias ib nrab-lub neej los ntawm lub cev tsis pub tshaj 3.5-6 teev, txawm tias siv ntev, metabolites tsis sib sau. Kev tshuaj xyuas qhia tau hais tias qhov kev kho no tshem tawm qhov mob taub hau, hauv cov neeg mob hawb pob bronchial, thaum noj, qhov zaus ntawm hmo ntuj thiab sawv ntxov raug txo qis, nrog rau lawv lub sijhawm thiab kev siv.
Tshuaj "Somnol": cov lus qhia, cov lus qhia rau kev siv
Puas yog lawv siv tshuaj li cas? Cov tshuaj "Somnol" cov lus qhia pom zoo siv nyob rau hauv rooj plaub ntawm:
- Pib pw tsaug zog tsis zoo (teeb meem pw tsaug zog, nquag awakenings thaum hmo ntuj, xwm txheej thiab ib ntus ntawm insomnia).
- Bronchial hawb pob, uas yog tus cwj pwm los ntawm kev tawm tsam thaum sawv ntxov. Noj ua ke nrog Theophylline.
- Kev pw tsaug zog tsis zoo hauv kev puas siab puas ntsws.
Txoj kev tswj hwm thiab noj ntau npaum li cas
Cov tshuaj "Somnol" yog noj ntawm qhov ncauj (cov lus qhia qhia qhov no). Nws raug nquahu kom siv cov tshuaj rau lub sijhawm luv luv, tsis pub ntau tshaj 4 lub lis piam, suav nrog lub sijhawm txo cov tshuaj. Nws tuaj yeem ua kom lub sijhawm kho mob tsuas yog tom qab rov ntsuas tus neeg mob tus mob.
Kev kho yuav tsum pib nrog qhov tsawg kawg nkaus, tsis muaj qhov ntau tshaj qhov tso cai ntau npaum li cas.
Tshuaj "Somnol" cov lus qhia rau kev siv pom zoo kom noj ua ntej yuav mus pw.
Thaum lub raum tsis ua haujlwm, kev kho mob yuav tsum pib ntawm ib nrabntsiav tshuaj (3.75 mg), txawm tias qhov tseeb tias zopiclone thiab metabolites tsis sib sau ua ke hauv lub raum tsis ua haujlwm.
Rau cov neeg mob hnub nyoog qis dua 65 xyoos, cov tshuaj "Somnol" cov lus qhia rau kev siv ib ntsiav tshuaj ntawm 7.5 mg pom zoo kom noj nws ib hnub ib zaug.
Nyob rau hauv rooj plaub ntawm daim siab ua haujlwm tsis zoo, kev kho mob pib nrog 3.75 mg tsis pub ntau tshaj ib hnub ib hnub, txij li lub sijhawm tshem tawm cov tshuaj hauv cov neeg mob no txo qis. Yog tias tsim nyog, qhov ntau npaum li cas tuaj yeem nce mus rau 7.5 mg, thaum tus neeg mob rhiab heev rau cov khoom xyaw ntawm cov tshuaj yuav tsum raug coj mus rau hauv tus account.
Nrog kev ua pa tsis ua haujlwm, kev kho mob, nrog rau lub siab ua haujlwm tsis zoo, pib nrog 3.75 mg tsis pub ntau tshaj ib zaug ib hnub. Cov txheej txheem no kuj tseem siv rau cov neeg muaj hnub nyoog 65 xyoos, yog tias tsim nyog, qhov ntau npaum yuav maj mam nce.
Txawm li cas los xij cov lus qhia rau kev siv Somnol, koob tshuaj txhua hnub yuav tsum tsis pub tshaj 7.5 mg. Nrog rau kev pw tsaug zog tsis zoo, kev kho mob txuas ntxiv tsis pub dhau 5 hnub, thiab rau qhov xwm txheej insomnia - tsis pub dhau 3 lub lis piam. Raws li rau daim ntawv mob ntev, nyob rau hauv cov xwm txheej zoo li no, kev kho mob tsuas yog txiav txim siab los ntawm tus kws kho mob tshwj xeeb.
Kev Sib Tham Tshuaj
Thaum Somnol tau noj ib txhij nrog neuroleptics, lwm yam hypnotics, anticonvulsants thiab sedatives, tranquilizers, antidepressants, opioid analgesics, tshuaj loog los yog erythromycin, cov nyhuv inhibitory ntawm lub hauv paus paj hlwb nce.
ThaumKev kho mob nrog cov tshuaj no txo cov concentration ntawm trimipramine hauv cov ntshav plasma thiab ua rau nws cov nyhuv tsis muaj zog.
Cov tshuaj "Somnol" cov lus qhia rau kev siv txwv tsis pub siv ib txhij nrog ethanol, vim qhov no tuaj yeem ua rau muaj kev nce ntxiv hauv cov nyhuv sedative ntawm cov tshuaj tseem ceeb - zopiclone.
Side effects
Raws li kev tshuaj xyuas ntawm cov kws kho mob tshwj xeeb thiab cov neeg mob, kev kho mob nrog Somnol tuaj yeem nrog cov teebmeem hauv qab no:
- Nervous system - qaug zog, ntxhov siab tom qab pw tsaug zog, mob taub hau, kiv taub hau, ntxhov siab vim, tsis muaj peev xwm nco qab cov xwm txheej tam sim no. Raws li qhov tshwm sim ntawm kev siv cov tshuaj tsaug zog no, qee zaum, cov tshuaj tiv thaiv paradoxical tshwm sim: nce kev chim siab, uas tuaj yeem txhim kho mus rau hauv kev ua phem, kev sib koom tes ntawm kev txav, kev nco nco tau cuam tshuam, kev ceev ntawm kev puas siab puas ntsws txo qis, kev nco qab yuav tsis meej pem, kev nyuaj siab tshwm sim.. Tom qab tus neeg mob nres noj Somnol (cov lus qhia, cov lus qhia rau kev siv tau muab rau hauv cov khoom no), nws yuav muaj kev cuam tshuam rau kev pw tsaug zog ib ntus.
- plab hnyuv - ib txwm ua haujlwm ntawm lub plab yog cuam tshuam, muaj xim hlau lossis iab saj tshwm hauv qhov ncauj.
- Cov ntsuas ntsuas - hauv cov ntshav ntshav, lub siab hloov pauv thiab alkaline phosphatase nce siab.
- Lub cev tiv thaiv kab mob - kev tsis haum tshuaj tshwm sim nyob rau hauv daim ntawv ntawm urticaria, khaus tawv nqaij, nyob rau hauv tsawg zaus - angioedema.
Contraindications rau kev siv
Siv tshuaj "Somnol" qhia tsis tso cai:
- Thaum muaj qhov tsis haum rau cov khoom xyaw.
- Hmo ua pa ntes.
- Tus kab mob autoimmune neuromuscular mob hnyav lossis mob hnyav.
- Ua pa, raum lossis siab tsis ua haujlwm.
- Kev cev xeeb tub.
- Thaum lactation.
Ntxiv rau, cov tshuaj tsaug zog no yog contraindicated rau cov menyuam yaus hnub nyoog qis dua 18 xyoo.
Tsis txhob hnov qab tias kev noj tshuaj tuaj yeem ua rau muaj kev quav tshuaj, kev txhim kho ntawm kev tshem tawm cov tsos mob kuj tau sau tseg, yog li nws raug txwv nruj kom nce koob tshuaj thiab sijhawm kho yam tsis tau sab laj nrog tus kws tshaj lij.
Ntau tshaj
Cov tsos mob ntawm ntau tshaj qhov pom zoo yog nyob ntawm seb qhov kev nyuaj siab ntawm lub hauv paus paj hlwb yog li cas. Feem ntau, qaug zog tshwm sim, tsawg zaus ib tug neeg poob rau hauv coma. Rau kev pab thawj zaug, tus neeg mob yuav tsum tau ntxuav lub plab, noj activated charcoal, yog tias tsim nyog, siv cov tsos mob hauv tsev kho mob. Hemodialysis nrog kev noj ntau dhau ntawm Somnol muaj qhov tsis zoo. Raws li tshuaj tua kab mob, koj tuaj yeem siv tshuaj los ntawm pab pawg tshuaj tua kab mob - Flumazenil.
Cov lus qhia tshwj xeeb
Cov tshuaj "Somnol" (cov lus qhia rau kev siv, tshuaj xyuas yog cov ncauj lus kom ntxaws hauv cov khoom no) yuav tsum tau ua tib zoo saib xyuas tshwj xeeb los ntawm cov neeg mob raum thiab mob siab thiab cov neeg laus. Thaum lub sij hawmKev kho mob yog txwv tsis pub siv dej cawv.
Raws li cawv cawv, cov nyhuv sedative ntawm cov tshuaj tsaug zog tau txhim kho. Kev siv cov tshuaj no ua rau qaug zog thaum sawv ntxov, uas cuam tshuam rau lub peev xwm tsav tsheb.
Kev txais tos "Somnol" tuaj yeem ua rau kev txhim kho ntawm lub hlwb thiab lub cev muaj zog. Cov xwm txheej zoo li no tsis tshua muaj tshwm sim, thaum txoj kev kho mob tsis pub dhau ib hlis. Yog tias qhov koob tshuaj thiab lub sijhawm ntawm cov tshuaj tau nce ntxiv ntawm nws tus kheej, qhov yuav tshwm sim ntawm kev vam meej nce ntxiv.
Qhov kev pheej hmoo tseem nce ntxiv thaum muab kev pab pw tsaug zog rau cov neeg uas muaj kev hloov pauv tus cwj pwm thiab keeb kwm ntawm kev haus dej ntau thiab kev vam khom rau qee yam tshuaj. Sudden discontinuation ntawm cov tshuaj tsaug zog nyob rau hauv cov neeg mob uas muaj kev vam khom yuav ua rau txoj kev loj hlob ntawm ib tug tshem tawm syndrome, uas yog yus muaj los ntawm cov tsos ntawm kev ntshai, mob taub hau thiab mob nqaij, tsis meej pem, thiab sab hauv. Muaj tsawg zaus, kev hloov ntawm tus cwj pwm tau pom, cov ceg qis qis qis dua, convulsions thiab hallucinations tshwm.
Tom qab kev kho mob tas mus li, kev pw tsaug zog tsis zoo yuav rov zoo dua, nrog rau ib qho ntawm cov tsos mob tshem tawm. Yog li ntawd, txoj kev kho yuav tsum ua kom tiav maj mam.
Yog tias, tom qab kev kho mob nrog Somnol, tseem muaj teeb meem ntawm kev tsaug zog lossis sawv thaum hmo ntuj, txhawm rau zam qhov pib ntawm anterograde amnesia, nws raug nquahu kom noj tshuaj tsaug zog.ua ntej yuav mus pw.
Siv thaum cev xeeb tub
Qhov tsis muaj ntaub ntawv kho mob yog qhov laj thawj tseem ceeb uas tsis kam noj Somnol hauv thawj peb lub hlis twg ntawm cev xeeb tub. Yog tias tsim nyog, nws raug tso cai siv cov tshuaj nyob rau lub hli dhau los ntawm kev xeeb tub, tab sis tsuas yog siv tsawg kawg nkaus xwb.
Zopiclone, uas yog ib feem ntawm Somnol, nyob rau lub peb hlis ntuj 3 ntawm cev xeeb tub tuaj yeem ua rau cov tsos mob ntawm hypothermia thiab hypotension hauv fetus, nws yuav tsum tau muab sau tseg tias yuav muaj kev nyuaj siab ua pa thiab tsaug zog ntau dhau. Thiab nyob rau thawj hnub ntawm lub neej, tus me nyuam mos yuav muaj cov tsos mob tshem tawm.
Yog hais tias cov tshuaj raug muab rau cov poj niam cev xeeb tub, lawv yuav tsum paub txog qhov yuav tsum tau mus nrhiav cov lus qhia ntawm tus kws kho mob tshwj xeeb los txiav txim seb puas yuav tsum tsis txhob kho thaum cev xeeb tub.
Vim tias cov tshuaj nquag "Somnol" raug tso tawm nrog niam mis, noj cov tshuaj thaum pub niam mis tuaj yeem ua rau tsis muaj zog thiab txo cov suab nrov hauv cov menyuam mos.
Txoj cai khaws cia thiab xa tawm hauv khw muag tshuaj
Khaws cov tshuaj tsaug zog hauv qhov chaw qhuav kom deb ntawm cov menyuam yaus, qhov chaw ncaj qha tshav ntuj tsis poob thiab qhov chaw huab cua kub tsis tshaj 25 degrees.
Koj tuaj yeem yuav tshuaj rau qhov nruab nrab ntawm 200 rubles thiab tsuas yog nrog tus kws kho mob cov tshuaj, nws tsis yog npaj rau kev siv tus kheej.
Tshuaj "Somnol": cov lus qhia rau kev siv, analogues
Kev tshuaj xyuas txog tshuaj tsaug zog yog qhov tsis sib xws. Ib txhia nco ntsoov tias thaum noj cov tshuaj, lawv muaj peev xwm tshem tau insomnia, mob taub hau thiab nquag pw tsaug zog. Lwm tus neeg mob xav tias cov tshuaj tsis kho lawv cov teeb meem.
Txawm li cas los xij, yog tias cov tshuaj tau noj raws li kws kho mob pom zoo, ua raws li cov lus qhia nruj me ntsis, cov tshuaj Somnol kho tau zoo nrog kev pw tsaug zog. Analogues, cov lus qhia rau kev siv uas yuav txawv me ntsis, tsis muaj txiaj ntsig zoo. Cov tshuaj nto moo tshaj plaws ntawm kev ua zoo ib yam suav nrog:
- Sovan;
- "Imovan";
- "Andante";
- "Selofen";
- Zopiclone;
- "Adorma";
- "Normason";
- "Sonata";
- Donormil;
- Piklon.