Ib qho tshuaj tiv thaiv kab mob siab, xaiv imidazoline receptor agonist, yog Physiotens. Kev tshuaj xyuas cov neeg mob hais tias cov cuab yeej pab txo qis cov ntshav qab zib thiab cov neeg rog rog.
Txhim kho ntshav siab
Kab mob ntawm lub plawv thiab cov hlab ntsha muaj kev cuam tshuam rau ntau tus neeg. Txawm li cas los xij, hauv cov poj niam, cov kev sib txawv no tshwm sim tom qab ntawm cov txiv neej. Tab sis lawv ua haujlwm nyuaj dua thiab muaj cov tsos mob ntawm cov ntshav siab, cov tsos mob tshwm sim ntau dua. Ntshav siab feem ntau tshwm sim nrog rau lwm yam pathologies: rog rog, ntshav qab zib mellitus, siab thiab lub raum txawv txav, lipid metabolism tsis ua haujlwm.
Nrog rau qhov nce hauv lub cev hnyav, muaj kev cuam tshuam ntawm SNS, uas yog lub ntsiab ua rau ntshav siab thiab tsim cov ntshav siab. Cov tshuaj hormones secreted los ntawm cov tsos mob ntawm lub paj hlwb pab txhawb nqa lub lumen ntawm cov hlab ntsha,Yog li ntawd, txhawm rau xa cov pa oxygen mus rau cov ntaub so ntswg thiab cov khoom nruab nrog cev, lub plawv yuav tsum tau thawb cov ntshav nrog kev siv zog, nyob rau hauv qhov siab, yog li tsim cov ntshav siab, uas yuav tsum tau kho nrog tshuaj. Ib qho tshuaj uas pab txo cov ntshav siab yog Physiotens.
Kev sib sau thiab tso tawm daim ntawv
Cov tshuaj yog tsim nyob rau hauv daim ntawv ntawm film-coated ntsiav tshuaj. Lub ntsiab active ingredient yog moxonindine. Cov khoom pabcuam suav nrog magnesium stearate, crospovidone, povidone, lactose monohydrate.
tshuaj muaj txiaj ntsig
Cov tshuaj nquag ntawm cov tshuaj muaj cov nyhuv hypotensive. Moxonidine nyob rau hauv lub hlwb qia hlwb xaiv nkoos rhiab receptors uas muaj kev koom tes nyob rau hauv lub reflex thiab tonic tswj ntawm lub paj hlwb cov tsos mob. Qhov tshwm sim yog qhov txo qis hauv peripheral cov tsos mob ua haujlwm thiab ntshav siab. Ntau cov kev tshawb fawb (placebo-tswj, randomized, ob-dig muag) ua pov thawj qhov ua tau zoo ntawm Physiotens. Cov neeg mob cov kev tshuaj xyuas tau lees paub tias cov tshuaj txawv ntawm lwm cov tshuaj tiv thaiv kab mob siab sympatholytic hauv qhov uas nws tsis ua rau lub qhov ncauj qhuav, thiab tsis muaj cov nyhuv sedative thaum siv nws.
Pharmacodynamics thiab pharmacokinetics
Tom qab kev tswj hwm sab hauv, cov tshuaj yog 90 feem pua ntxhiab los ntawm txoj hnyuv. Qhov siab tshaj plaws ntawm cov tshuaj nquag hauv cov ntshav plasmapom tom qab ib teev. Noj mov tsis cuam tshuam rau pharmacokinetics ntawm moxonidine.
Lub ntsiab metabolite ntawm cov tshuaj nquag yog lub cev qhuav dej moxonidine, nrog rau guanidine derivatives. Ib nrab-lub neej ntawm moxonidine tshwm sim nyob rau hauv 2.5 teev, thiab tom qab ib hnub, lub ntsiab yog 90% tawm los ntawm ob lub raum thiab cov hnyuv.
Hauv cov neeg mob ntshav siab, piv nrog cov neeg noj qab haus huv, tsis muaj kev hloov pauv hauv cov tshuaj pharmacokinetics ntawm moxonidine tau raug sau tseg. Cov kev ntsuas kinetic me ntsis tuaj yeem hloov pauv hauv cov neeg mob laus, uas cuam tshuam nrog kev txo qis ntawm moxodinine metabolism, nrog rau nws cov bioavailability ntau dua.
Vim tias tsis muaj kev tshawb fawb pharmacokinetic, kev siv tshuaj hauv cov neeg mob hnub nyoog qis dua feem ntau tsis pom zoo.
Cov tshuaj "Physiotens" cov lus qhia rau kev siv
Kev tshuaj xyuas cov neeg mob hais tias cov tshuaj yuav tsum tau noj, tsis hais noj mov. Feem ntau cov tshuaj yog siv nyob rau hauv thawj zaug ib hnub koob tshuaj ntawm 200 mcg. Qhov siab tshaj plaws ib ntim ntawm cov tshuaj yuav tsum tsis txhob ntau tshaj 400 mcg, ib hnub twg muab faib ua ob koob tshuaj yuav tsum tsis txhob ntau tshaj 600 mcg. Cov neeg mob uas muaj lub plawv tsis ua hauj lwm nruab nrab mus rau qhov hnyav uas nyob rau hauv hemodialysis tau pom zoo kom noj txog 200 mcg ntawm cov tshuaj ib hnub. Nrog kev ua siab ntev, qhov ntim ntawm cov tshuaj tuaj yeem ua ob npaug.
Ntau tshaj
Nrog kev siv tshuaj ntau dhau, ntau yam tsos mob tshwm sim. Yog li, cov ntsiav tshuaj rau siab "Physiotens" (kev tshuaj xyuas qhiarau qhov no) tuaj yeem ua rau mob taub hau, tsaug zog, sedation. Yog tias qhov ntau npaum li cas, lub siab tuaj yeem poob qis, qhov mob tshwm sim hauv thaj tsam epigastric, qhov ncauj qhuav, bradycardia, ntuav, asthenia, qaug zog, kiv taub hau. Tsis tas li ntawd, cov neeg mob tuaj yeem cuam tshuam los ntawm hyperglycemia, tachycardia, nrog rau lub sijhawm luv luv ntawm qhov siab.
Tsis muaj tshuaj tiv thaiv tshwj xeeb tau tsim los kho cov tsos mob ntawm kev noj ntau dhau. Nrog rau cov hlab ntsha hypotension, nws yog ib qho tsim nyog los qhia dopamine thiab nce cov kua dej hauv lub cev. Cov tsos mob ntawm bradycardia tuaj yeem kho nrog atropine. Nyob rau hauv cov ntaub ntawv ntawm overdose, nws raug pom zoo kom txo los yog tshem tawm arterial paradoxical hypertension los ntawm kev siv alpha-adrenergic receptor antagonists.
Kev Sib Tham Tshuaj
Kev sib xyaw tshuaj tsis yog ib txwm muab qhov tseem ceeb. Txawm li cas los xij, thaum noj ob lossis ntau dua cov tshuaj, tej zaum yuav muaj qhov tsis muaj zog lossis ua kom muaj zog ntawm kev sib nrig sib. Hauv thawj kis, cov tshuaj yuav tsis muab qhov kev xav tau, hauv qhov xwm txheej thib ob muaj kev pheej hmoo ntawm kev siv tshuaj ntau dhau thiab txawm tias muaj tshuaj lom.
Yog li, thaum ua ke nrog kev siv tshuaj tiv thaiv kab mob siab (thiazide diuretics, calcium qeeb channel blockers) nrog cov tshuaj "Physiotens" (kev tshuaj xyuas ceeb toom txog qhov no), cov nyhuv hypotensive ntxiv tuaj yeem txhim kho. Kev siv ib txhij ntawm tricyclic antidepressants txo cov txiaj ntsig ntawm cov tshuaj tiv thaiv kab mob hauv nruab nrab, yog li lawv yuav tsum tsis txhob siv ua ke nrog cov tshuaj. Physiotens.
Ntxiv rau, cov cuab yeej tuaj yeem txhim kho kev paub tsis meej hauv cov neeg mob noj tshuaj "Lorazepam". Kev siv ua ke nrog benzodiazepines tuaj yeem ua rau muaj kev nce ntxiv hauv cov nyhuv sedative. Thaum noj nrog Digoxin, Glibenclamide, Hydrochlorothiazide, tsis muaj kev sib cuam tshuam ntawm pharmacokinetic.
Siv thaum cev xeeb tub
Ntau yam tshuaj muaj qhov tsis zoo rau tus menyuam hauv plab lossis embryo, ua rau qee qhov ua rau tus menyuam tsis zoo. Tsis tas li ntawd, cov khoom siv ntawm cov tshuaj noj nrog niam cov kua mis muaj peev xwm nkag mus rau tus menyuam mos lub cev thiab ua rau nws. Yog li ntawd, thaum cev xeeb tub thiab lactation, yuav tsum noj tshuaj nrog ceev faj heev.
Physiotens tsis muaj qhov zam. Nws qhov kev txais tos tsuas yog tso cai tom qab kev sab laj nrog tus kws kho mob tshwj xeeb, ua tib zoo ntsuas qhov txiaj ntsig tau rau leej niam thiab ua rau tus menyuam raug mob. Txij li thaum cov khoom xyaw nquag nkag mus rau hauv cov kua mis, nws yog ib qho tsim nyog yuav tsum tsis txhob siv los yog tsis pub mis rau menyuam thaum pub niam mis.
Kev tshawb fawb tshawb fawb txog tsiaj txhu tsis tau qhia txog qhov cuam tshuam ncaj qha lossis tsis ncaj ntawm cov tshuaj ntawm cev xeeb tub, embryonic (embryonic) lossis kev loj hlob tom qab yug menyuam.
Side effect
Zoo li feem ntau cov tshuaj, Physiotens ntsiav tshuaj (kev tshuaj xyuas qhia qhov no) ua rau muaj kev tsis zoo ntawm lub cev. Qhov no feem ntau tshwm sim thaum sivnyob rau hauv ntau qhov ntau, rau lub sij hawm ntev los yog nrog ib tus neeg intolerance rau cov khoom xyaw nquag.
Lub paj hlwb ua haujlwm rau kev siv tshuaj nrog mob taub hau, tsaug zog lossis pw tsaug zog, kiv taub hau. Cov tsos mob no tau pom ntau zaus. Los ntawm ib sab ntawm lub plawv thiab vascular system, tsis zoo tshwm sim tshwm sim nyob rau hauv tsawg zaus, manifested los ntawm ib tug ntse poob siab, orthostatic hypotension. Tsis tas li ntawd, cov neeg mob tom qab noj cov tshuaj muaj lub qhov ncauj qhuav, xeev siab, lawv yuav muaj kev cuam tshuam dermatological hauv daim ntawv ntawm angioedema, khaus lossis pob khaus ntawm daim tawv nqaij. Thaum muaj kev phiv tshuaj, cov tshuaj yuav tsum tsis txhob muab tso tseg; cov tsos mob tsis zoo feem ntau ploj tom qab peb lub lis piam ntawm kev siv. Txawm li cas los xij, tseem yuav tsum tau hu rau tus kws tshaj lij.
YContraindications
Tsis yog txhua kis koj tuaj yeem noj tshuaj "Physiotens". Kev tshuaj xyuas cov kws kho mob hais tias nws tsis pom zoo kom noj tshuaj thaum:
- nthuav tawm bradycardia (lub plawv dhia qis dua 50 tus neeg ntaus ib feeb);
- SSSU;
- hereditary galactose (glucose) intolerance lossis malabsorption
- Ylactase deficiency;
- hypersensitivity rau lub Cheebtsam ntawm cov tshuaj;
Ua tib zoo sau cov tshuaj nyob rau theem kawg lossis lub raum tsis ua haujlwm hnyav, cov neeg mob uas muaj hemodialysis, nrog lub siab ua haujlwm hnyav.
Physiotens ntsiav tshuaj:indications rau kev siv, tshuaj xyuas, cov lus qhia tshwj xeeb
Qhov kev kuaj mob tseem ceeb uas cov kws kho mob sau tshuaj yog arterial hypertension. Nws yuav tsum tau nco ntsoov tias thaum lub sij hawm kho nws yog tsim nyog los saib xyuas lub xeev ntawm cov ntshav siab, ECG thiab lub plawv dhia. Yog tias koj xav tau tshem tawm cov tshuaj, ces qhov no yuav tsum maj mam ua.
Lub cuab yeej tsis cuam tshuam rau lub peev xwm tsav tsheb thiab kev thauj mus los. Txawm li cas los xij, cov tshuaj "Physiotens" (cov neeg mob tshuaj xyuas qhia qhov no) yuav tsum tau ceev faj, vim nws tuaj yeem ua rau kiv taub hau thiab tsaug zog. Qhov tseeb no yuav tsum raug coj mus rau hauv tus account los ntawm cov neeg koom nrog hauv cov haujlwm txaus ntshai uas yuav tsum tau ua tib zoo mloog.
khaws cia, analogues thiab nqe
Cov tshuaj yuav tsum khaws kom deb ntawm cov menyuam yaus. Yog tias cov cai khaws cia tau pom zoo (kub txog 25 ° C, qhov chaw tsaus tsaus), cov tshuaj yuav tsis poob nws cov khoom siv tshuaj rau ob xyoos. Koj tuaj yeem yuav cov tshuaj "Physiotens" (kev tshuaj xyuas kom paub meej qhov no) los ntawm cov tshuaj hauv khw muag tshuaj. Tus nqi ntawm ib pob ntawm cov ntsiav tshuaj (0.2 mg) yog 275 rubles. Yog tias vim qee yam tsis muaj tshuaj hauv lub tsev muag tshuaj, koj yuav tsum tau saib cov analogues: Cint, Moxonitex, Moxonidine, Moxogamma.
Reviews about the drug "Physiotens"
Ntau tus neeg mob hais txog cov tshuaj no yog ib qho tshuaj zoo. Cov neeg hais tias lawv tau noj ntau xyoo, cov tshuaj txo cov ntshav siab zoo, thaumtsis muaj kev phiv. Qee tus cwj pwm tus nqi siab ntawm Physiotens ntsiav tshuaj rau qhov tsis zoo. Kev tshuaj xyuas qhia tau tias muaj kev sib raug zoo nrog lwm cov tshuaj hypertensive.
