Txhua qhov teeb meem ntawm cov hlab plawv yuav tsum tau saib xyuas ntawm tus kws kho plawv. Yog tias muaj cov tsos mob tsis zoo tshwm sim, koj yuav tsum nrhiav kev pab tam sim ntawm tus kws kho mob tshwj xeeb. Nrov ntawm cov kws kho mob yog cov tshuaj "Propanorm". Analogues ntawm cov tshuaj no kuj siv heev heev. Cov kws tshaj lij qhia kom ua tib zoo kawm cov lus qhia ua ntej pib kev kho mob.
Form and composition
Cov tshuaj tau nthuav tawm hauv daim ntawv ntawm biconvex puag ncig dawb ntsiav tshuaj. Cov khoom xyaw tseem ceeb yog propafenone hydrochloride. Raws li excipients, microcrystalline granulated cellulose, sodium lauryl sulfate, titanium dioxide, magnesium stearate, thiab copovidone yog siv. Cov tshuaj mus muag hauv ib pob ntawv.
Cov tshuaj "Propanorm" belongs rau pab pawg ntawm cov tshuaj arrhythmic. Kev tshuaj xyuas ntawm cov kws kho plawv qhia tau hais tias cov khoom muaj txiaj ntsig tseem ceeb thaiv cov kab nrawm nrawm. Cov nyhuv tshuaj loog hauv zos, uas yog muab los ntawm cov tshuaj, xyaum ua raws liprocaine kev ua si. Qhov kev txiav txim ntawm propafenone pib hauv ib teev tom qab noj cov ntsiav tshuaj sab hauv. Qhov siab tshaj plaws yog ua tiav tom qab 3 teev. Cov nyhuv ntawm cov tshuaj yuav kav ntev li 12 teev.
Kev qhia
Cov tshuaj no feem ntau tau sau tseg rau qhov tshwm sim ntawm ventricular thiab supraventricular extrasystoles. Txhawm rau kom tsis txhob muaj kev txhim kho ntawm tus kab mob, cov ntsiav tshuaj kuj tuaj yeem muab tshuaj rau lub hom phiaj ntawm kev tiv thaiv. Cov tshuaj kuj tau qhia rau kev kho mob ntawm qhov txawv txav xws li paroxysmal plawv atherosclerosis abnormalities, ventricular-atrial tachycardia, monomorphic ventricular tachycardia.
Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo yog muab cov tshuaj Propanom nrog ceev faj. Analogues kuj yuav tsum tau noj tom qab kev sab laj ua ntej nrog tus kws kho mob. Feem ntau, cov tshuaj tuaj yeem raug sau rau ntawm qhov txo qis (20-30% ntawm tus nqi ib txwm). Cov neeg mob uas hnyav lub cev hnyav, nrog rau cov neeg mob hnub nyoog tshaj 70 xyoo, raug kho kom nruj raws li kev saib xyuas kev kho mob. Thawj cov tshuaj noj yog nyob rau hauv ECG tswj.
Cov poj niam cev xeeb tub tuaj yeem raug sau npe Propanorm yog tias qhov txiaj ntsig xav tau rau leej niam tshaj qhov muaj feem cuam tshuam rau tus menyuam. Qhov kev txiav txim siab ntawm qhov ntau npaum li cas yog ua los ntawm tus kws kho plawv raws li tus kheej tus yam ntxwv ntawm tus neeg mob lub cev.
YContraindications
Koj yuav tsum tsis txhob noj cov tshuaj Propanorm yam tsis muaj kws kho mob pom zoo. Kev tshuaj xyuas ntawm cardiologists qhia tau hais tias cov tshuaj muaj ntau contraindications. Nyob rau hauv tsis muaj cov ntaub ntawv yuav tsum tau noj tshuaj nrog xws lideviations, xws li arterial hypotension, mob plawv tsis ua hauj lwm, bradycardia, myocardial infarction, cardiogenic poob siab. Ua ntej pib kho, tus neeg mob yuav tsum tau kuaj xyuas tag nrho lub cev. Qhov no yuav pab kom tsis txhob muaj qhov tshwm sim tsis zoo thaum lub sijhawm kho.
Muaj kev txwv hnub nyoog. Propanorm ntsiav tshuaj tsis tuaj yeem muab rau cov neeg mob me. Kev tshuaj xyuas ntawm cov kws kho plawv qhia tau hais tias rau cov menyuam yaus muaj cov tshuaj sib cais uas muaj kev cuam tshuam me me rau cov hlab plawv.
Cov lus qhia tshwj xeeb
ntsiav tshuaj "Propanorm" feem ntau yog muab rau cov neeg mob hauv tsev kho mob. Qhov no yog vim lub fact tias nyob rau hauv lub chav kawm ntawm kev kho mob nws yog ib lub sij hawm yuav tsum tau saib xyuas kev ua hauj lwm ntawm lub plawv ntawm ECG. Qhov no tseem ceeb tshwj xeeb tshaj yog thaum pib kho. Kev saib xyuas zoo yog them rau cov neeg laus uas nws qhov hnyav tshaj 80 kg. Tsis txhob hnov qab tias propafenone muaj cov nyhuv arrhythmogenic. Hauv qhov no, tus neeg mob txoj kev noj qab haus huv nyob rau theem pib ntawm kev kho mob yuav ua rau tsis zoo.
Cov neeg mob lub siab tsis ua haujlwm yuav tsum pib noj cov tshuaj tom qab kev sab laj nrog kws kho mob ua ntej. Hauv cov neeg mob zoo li no, bioavailability ntawm propafenone tuaj yeem nce 70%. Hauv qhov no, kev mob tshwm sim feem ntau tshwm sim. Qhov ntau npaum li cas rau cov neeg mob uas lub siab ua haujlwm tsis zoo yog txo. Tsis tas li ntawd, cov ntsuas ntsuas ntsuas tsis tu ncua.
Lub sijhawm kho nrog Propanorm, nws raug nquahu kom tsis txhob noj.tsav tsheb lossis lwm yam kev thauj mus los. Cov neeg mob yuav muaj kev txhawj xeeb lossis kiv taub hau.
KOJ
Kev kho mob yog teem los ntawm kws kho plawv ib leeg rau txhua tus neeg mob raws li kev kho mob tshwm sim ntawm ib tus kab mob. Lub bioavailability ntawm cov tshuaj yog nce yog tias noj tom qab noj mov. Cov ntsiav tshuaj tau nqos tag nrho nrog ib qho me me ntawm cov kua. Thawj koob tshuaj yuav yog 150 mg txhua 8 teev (peb zaug hauv ib hnub). Tus nqi txhua hnub yuav tsum tsis pub tshaj 450 mg. Maj mam cov koob tshuaj nce ntxiv. Koj yuav tsum tsis txhob noj cov ntsiav tshuaj Propanorm ntawm koj tus kheej. Kev tshuaj xyuas tus neeg mob nco ntsoov tias tsuas yog ib tus kws kho mob uas tsim nyog tuaj yeem txiav txim siab qhov xav tau ntau npaum li cas. Qhov nyiaj pub tshaj txhua hnub nyob rau nruab nrab ntawm chav kho mob tuaj yeem ncav cuag 900 mg (sib faib ua peb koob).
Cov neeg mob laus hnyav dua 70 kg, qhov ntau npaum li cas txo. Hauv ib lub sijhawm, lawv tuaj yeem noj tsis pub ntau tshaj 100 mg. Hauv qhov no, cov cai niaj hnub yog 300 mg. Hauv chav kho mob, cov neeg mob ib ntus tau soj ntsuam lub plawv dhia ntawm lub tshuab ECG.
Cov neeg mob uas muaj lub siab ua haujlwm tsis zoo yuav raug muab tshuaj noj uas tsuas yog 30% ntawm tus qauv. Yog tias muaj qhov zoo sib xws, tus nqi txhua hnub yuav raug txo me ntsis. Kev kho mob tshwm sim hauv tsev kho mob.
Ntau tshaj
Nws tsuas yog siv tus neeg mob ob zaug ntawm qhov pom zookws kho mob, raws li nws hnov cov tsos mob ntawm intoxication. Yog li ntawd, nruj me ntsis raws li kev pom zoo ntawm tus kws kho mob tshwj xeeb, nws tsim nyog siv Propanorm ntsiav tshuaj. Kev tshuaj xyuas ntawm kws kho mob qhia tias kiv taub hau thiab xeev siab tshwm sim thawj zaug. Tsis tas li ntawd, tus neeg mob yuav hnov qhov ncauj qhuav, nws cov ntshav txo qis.
Kev kho mob ntau dhau tuaj yeem tshwm sim hauv tsev kho mob nkaus xwb. Ua ntej ntawm tag nrho cov, gastric lavage yog ua. Nyob rau hauv lub neej yav tom ntej, symptomatic therapy muab tau zoo. Tus neeg mob tau muab tshuaj Dobutamine thiab Diazepam. Nyob rau hauv cov xwm txheej nyuaj tshaj plaws, kev ua pa ntawm lub ntsws yog ua tiav, nrog rau hauv siab compressions.
Side effects
Cov tsos mob tsis zoo kuj tuaj yeem tshwm sim yog tias tus neeg mob noj cov tshuaj raws li qhov pom zoo los ntawm tus kws kho mob. Nws tsim nyog kawm tag nrho cov ntaub ntawv hais txog cov tshuaj ua ntej koj pib noj cov ntsiav tshuaj Propanorm. Cov lus qhia rau kev siv, tshuaj xyuas - tag nrho cov no tuaj yeem tau txais los ntawm tus kws kho mob tuaj koom. Feem ntau, cov kev mob tshwm sim tshwm sim ntawm ib feem ntawm lub plab zom mov thaum pib ntawm chav kawm. Tus neeg mob yuav hnov xeev siab lossis tsis qab los noj mov. Muaj tsawg zaus, raws plab tau pom. Tag nrho cov tsos mob no thim rov qab thiab tsis xav tau kev kho mob.
Rau ib feem ntawm lub paj hlwb hauv nruab nrab, cov kev mob tshwm sim xws li kiv taub hau, mob hauv lub tuam tsev, tsis meej pem, thiab kev pw tsaug zog tuaj yeem pom. Thaum pib ntawm kev kho mob, tus neeg mob yuav hnov qhov qaug zog ntau dhau. Tag nrho cov no tsis yog vim li cas thiaj li tshem tawm cov tshuaj "Propanorm". Kev tshuaj xyuas ntawm cov kws kho plawv qhia tau hais tias txhua yam kev mob tshwm sim ploj hauv ib lub lis piam tom qab pibkev kho mob.
Ua tib zoo saib xyuas kev tsis haum tshuaj. Tus neeg mob yuav pom cov pob khaus ntawm nraub qaum thiab caj npab. o ntawm cov ceg thiab lub ntsej muag yuav tsum ceeb toom. Qhov txaus ntshai tshaj plaws yog Quincke's edema. Thaum tus neeg mob pom tias thaj chaw caj dab o, nws yuav tsum hu rau lub tsheb thauj neeg mob tam sim ntawd.
Kev Sib Tham Tshuaj
Ua ntej siv, koj yuav tsum ua tib zoo kawm cov lus qhia rau cov tshuaj "Propanorm". Analogues kuj tseem siv tom qab qhia meej tag nrho cov ntaub ntawv tsim nyog. Qhov tseeb yog tias cov tshuaj antiarrhythmic tsis sib haum nrog txhua yam tshuaj. Tsis muaj ib qho twg yog cov ntsiav tshuaj siv ua ke nrog lidocaine. Qhov piv txwv no txhim kho cov nyhuv cardiodepressive.
Propanorm ntsiav tshuaj tsis tau noj ua ke nrog Varvarin. Los ntawm kev thaiv cov metabolism, cov nyhuv ntawm cov tshuaj kawg tau txhim kho zoo. Nws kuj tsis pom zoo kom siv tshuaj antiarrhythmic nyob rau hauv parallel nrog tshuaj loog hauv zos. Qhov kev pheej hmoo ntawm kev puas tsuaj rau lub hauv nruab nrab lub paj hlwb nce.
Tsis txhob noj ua ke nrog cov tshuaj uas ua rau lub hlwb hematopoiesis, tshuaj "Propanorm". Cov lus qhia rau kev siv (cov ntsiav tshuaj) hais tias xws li kev sib xyaw ua ke tuaj yeem ua rau kev txhim kho myelosuppression.
Analogues
Yuav ua li cas yog tias koj nrhiav tsis tau Propanorm ntsiav tshuaj ntawm lub tsev muag tshuaj? Analogues, tshuaj xyuas uas yog qhov zoo, tus kws kho plawv yuav tuaj yeem tawm tswv yim. Cov tshuaj "Propafenone" yog nrov. Qhov no yog ib tus neeg sawv cev antiarrhythmic uas tuaj yeem sau rau qhov noCov kab mob xws li supraventricular tachycardia, WPW syndrome, thiab lwm yam. Cov tshuaj no tsis raug muab rau cov neeg mob me, nrog rau cov poj niam thaum cev xeeb tub.
"Ritmonorm" yog lwm cov tshuaj tiv thaiv kab mob uas cov kws kho plawv hais tau zoo. Nws yog siv feem ntau hauv tsev kho mob. Yuav tsis muaj peev xwm yuav tshuaj yam tsis tau sau ntawv.
Reviews about the drug "Propanorm"
Cov kws kho plawv nco ntsoov tias cov lus qhia siv rau kev npaj Propanorm yuav tsum tau kawm. Peb tau nthuav tawm ib daim duab ntawm cov tshuaj thiab tag nrho cov ntaub ntawv hais txog nws nyob rau hauv tsab xov xwm. Hauv cov neeg mob uas paub txog qhov ua tau tshwm sim thiab contraindications, kev xav tsis zoo ntawm cov tshuaj tsis tshwm sim. Cov neeg mob uas raug kho hauv tsev kho mob, nco ntsoov tias qhov txiaj ntsig zoo ntawm kev siv tshuaj "Propanorm" yog pom tom qab ib lub lim tiam.